|Other Names||E3 ubiquitin-protein ligase ARIH2, ARI-2, Protein ariadne-2 homolog, 632-, Triad1 protein, ARIH2, ARI2, TRIAD1|
|Format||Synthetic peptide was lyophilized with 100% acetonitrile and is supplied as a powder. Reconstitute with 0.1 ml DI water for a final concentration of 1 mg/ml.|
|Storage||Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C.|
|Precautions||This product is for research use only. Not for use in diagnostic or therapeutic procedures.|
|Function||E3 ubiquitin-protein ligase mediating 'Lys-48'-and 'Lys- 63'-linked polyubiquitination and subsequent proteasomal degradation of modified proteins. May play a role in myelopoiesis.|
|Cellular Location||Nucleus. Cytoplasm.|
|Tissue Location||Widely expressed with higher expression in granulocytes.|
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Provided below are standard protocols that you may find useful for product applications.
E3 ubiquitin-protein ligase mediating 'Lys-48'-and 'Lys-63'-linked polyubiquitination and subsequent proteasomal degradation of modified proteins. May play a role in myelopoiesis.
Marteijn, J.A., et al. Leukemia 23(8):1480-1489(2009)Marteijn, J.A., et al. Blood 110(9):3128-3135(2007)Matsuoka, S., et al. Science 316(5828):1160-1166(2007)Marteijn, J.A., et al. Blood 106(13):4114-4123(2005)Stelzl, U., et al. Cell 122(6):957-968(2005)
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