|Other Names||Metalloreductase STEAP1, 1161-, Six-transmembrane epithelial antigen of prostate 1, STEAP1, PRSS24, STEAP|
|Format||Synthetic peptide was lyophilized with 100% acetonitrile and is supplied as a powder. Reconstitute with 0.1 ml DI water for a final concentration of 1 mg/ml.|
|Storage||Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C.|
|Precautions||This product is for research use only. Not for use in diagnostic or therapeutic procedures.|
|Function||Metalloreductase that has the ability to reduce both Fe(3+) to Fe(2+) and Cu(2+) to Cu(1+). Uses NAD(+) as acceptor (By similarity).|
|Cellular Location||Endosome membrane; Multi-pass membrane protein|
|Tissue Location||Ubiquitously expressed. Highly expressed in prostate tumors.|
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Provided below are standard protocols that you may find useful for product applications.
This gene is predominantly expressed in prostate tissue,and is found to be upregulated in multiple cancer cell lines. Thegene product is predicted to be a six-transmembrane protein, andwas shown to be a cell surface antigen significantly expressed atcell-cell junctions.
Valenti, M.T., et al. J. Endocrinol. Invest. 33(4):244-249(2010)Johnatty, S.E., et al. PLoS Genet. 6 (7), E1001016 (2010) :Vaghjiani, R.J., et al. Tissue Eng Part A 15(8):2073-2083(2009)Mavaddat, N., et al. Cancer Epidemiol. Biomarkers Prev. 18(1):255-259(2009)Maia, C.J., et al. Endocrine 34 (1-3), 108-116 (2008) :
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