|Other Names||Protein phosphatase 1G, Protein phosphatase 1C, Protein phosphatase 2C isoform gamma, PP2C-gamma, Protein phosphatase magnesium-dependent 1 gamma, PPM1G, PPM1C|
|Format||Synthetic peptide was lyophilized with 100% acetonitrile and is supplied as a powder. Reconstitute with 0.1 ml DI water for a final concentration of 1 mg/ml.|
|Storage||Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C.|
|Precautions||This product is for research use only. Not for use in diagnostic or therapeutic procedures.|
|Cellular Location||Cytoplasm. Membrane; Lipid-anchor|
|Tissue Location||Widely expressed. Most abundant in testis, skeletal muscle, and heart|
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Provided below are standard protocols that you may find useful for product applications.
The protein encoded by this gene is a member of the PP2Cfamily of Ser/Thr protein phosphatases. PP2C family members areknown to be negative regulators of cell stress response pathways.This phosphatase is found to be responsible for thedephosphorylation of Pre-mRNA splicing factors, which is importantfor the formation of functional spliceosome. Studies of a similargene in mice suggested a role of this phosphatase in regulatingcell cycle progression.
Dick, D.M., et al. Am. J. Med. Genet. B Neuropsychiatr. Genet. 153B (6), 1179-1188 (2010) :Suh, E.J., et al. Biochem. Biophys. Res. Commun. 386(3):467-470(2009)Petri, S., et al. J. Cell Biol. 179(3):451-465(2007)Allemand, E., et al. Nat. Struct. Mol. Biol. 14(7):630-638(2007)Matsuoka, S., et al. Science 316(5828):1160-1166(2007)
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