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PTPRE Antibody (N-term) Blocking Peptide

Synthetic peptide

Product Information
Primary Accession P23469
Clone Names 100525053
Peptide ID 100525053
Additional Information
Gene ID 5791
Other Names Receptor-type tyrosine-protein phosphatase epsilon, Protein-tyrosine phosphatase epsilon, R-PTP-epsilon, PTPRE
Format Synthetic peptide was lyophilized with 100% acetonitrile and is supplied as a powder. Reconstitute with 0.1 ml DI water for a final concentration of 1 mg/ml.
StorageMaintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C.
PrecautionsThis product is for research use only. Not for use in diagnostic or therapeutic procedures.
Protein Information
Function Isoform 1 plays a critical role in signaling transduction pathways and phosphoprotein network topology in red blood cells. May play a role in osteoclast formation and function (By similarity).
Cellular Location Isoform 1: Cell membrane; Single-pass type I membrane protein Isoform 3: Cytoplasm.
Tissue Location Expressed in giant cell tumor (osteoclastoma rich in multinucleated osteoclastic cells)
Research Areas
Citations (0)

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The protein encoded by this gene is a member of theprotein tyrosine phosphatase (PTP) family. PTPs are known to besignaling molecules that regulate a variety of cellular processesincluding cell growth, differentiation, mitotic cycle, andoncogenic transformation. Two alternatively spliced transcriptvariants of this gene have been reported, one of which encodes areceptor-type PTP that possesses a short extracellular domain, asingle transmembrane region, and two tandem intracytoplasmiccatalytic domains; Another one encodes a PTP that contains adistinct hydrophilic N-terminus, and thus represents anonreceptor-type isoform of this PTP. Studies of the similar genein mice suggested the regulatory roles of this PTP in RAS relatedsignal transduction pathways, cytokines induced SATA signaling, aswell as the activation of voltage-gated K+ channels. [provided byRefSeq].


Rose, J.E., et al. Mol. Med. 16 (7-8), 247-253 (2010) :Joslyn, G., et al. Alcohol. Clin. Exp. Res. 34(5):800-812(2010)Barr, A.J., et al. Cell 136(2):352-363(2009)Kraut-Cohen, J., et al. J. Biol. Chem. 283(8):4612-4621(2008)Tremblay, K., et al. PLoS ONE 3 (8), E2907 (2008) :

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$ 80.00
Cat# BP14405a
(40 western blots)
Availability: In Stock
Bulk Size
Seasonal Special on Bulk Order
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