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ZIC4 Antibody (N-term) Blocking Peptide
Synthetic peptide
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
| Primary Accession | Q8N9L1 |
|---|---|
| Clone Names | 100525082 |
| Gene ID | 84107 |
|---|---|
| Other Names | Zinc finger protein ZIC 4, Zinc finger protein of the cerebellum 4, ZIC4 |
| Format | Peptides are lyophilized in a solid powder format. Peptides can be reconstituted in solution using the appropriate buffer as needed. |
| Storage | Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C. |
| Precautions | This product is for research use only. Not for use in diagnostic or therapeutic procedures. |
| Name | ZIC4 |
|---|---|
| Function | Binds to DNA. |
| Cellular Location | Nucleus. |
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Provided below are standard protocols that you may find useful for product applications.
Background
This gene encodes a member of the ZIC family of C2H2-typezinc finger proteins. Members of this family are important duringdevelopment, and have been associated with X-linked visceralheterotaxy and holoprosencephaly type 5. This gene is closelylinked to the gene encoding zinc finger protein of the cerebellum1, a related family member on chromosome 3. Heterozygous deletionof these linked genes is involved in Dandy-Walker malformation,which is a congenital cerebellar malformation. Multiple transcriptvariants have been identified for this gene.
References
Grinberg, I., et al. Clin. Genet. 67(4):290-296(2005)Jaster, J.H. Neurology 63 (7), 1339 (2004) :Grinberg, I., et al. Nat. Genet. 36(10):1053-1055(2004)Ohtsuka, M., et al. Genomics 83(6):1063-1071(2004)Bataller, L., et al. Neurology 62(5):778-782(2004)
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