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ADORA1 Antibody (C-term) Blocking Peptide
Synthetic peptide
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
| Primary Accession | P30542 |
|---|---|
| Clone Names | 100525136 |
| Gene ID | 134 |
|---|---|
| Other Names | Adenosine receptor A1, ADORA1 |
| Format | Peptides are lyophilized in a solid powder format. Peptides can be reconstituted in solution using the appropriate buffer as needed. |
| Storage | Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C. |
| Precautions | This product is for research use only. Not for use in diagnostic or therapeutic procedures. |
| Name | ADORA1 |
|---|---|
| Function | Receptor for adenosine. The activity of this receptor is mediated by G proteins which inhibit adenylyl cyclase. |
| Cellular Location | Cell membrane; Multi-pass membrane protein |
Thousands of laboratories across the world have published research that depended on the performance of antibodies from Abcepta to advance their research. Check out links to articles that cite our products in major peer-reviewed journals, organized by research category.
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Provided below are standard protocols that you may find useful for product applications.
Background
The protein encoded by this gene is an adenosine receptorthat belongs to the G-protein coupled receptor 1 family. There are3 types of adenosine receptors, each with a specific pattern ofligand binding and tissue distribution, and together they regulatea diverse set of physiologic functions. The type A1 receptorsinhibit adenylyl cyclase, and play a role in the fertilizationprocess. Animal studies also suggest a role for A1 receptors inkidney function and ethanol intoxication. Transcript variants withalternative splicing in the 5' UTR have been found for this gene.
References
Lane, J.R., et al. Biochem. Pharmacol. 80(8):1180-1189(2010)Bailey, S.D., et al. Diabetes Care 33(10):2250-2253(2010)Wagner, A.K., et al. Epilepsy Res. 90(3):259-272(2010)Ruano, G., et al. Pharmacogenomics 11(7):959-971(2010)Pinheiro, A.P., et al. Am. J. Med. Genet. B Neuropsychiatr. Genet. 153B (5), 1070-1080 (2010) :
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