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PTGIR Antibody (Center) Blocking Peptide
Synthetic peptide
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
| Primary Accession | P43119 |
|---|---|
| Clone Names | 100525141 |
| Gene ID | 5739 |
|---|---|
| Other Names | Prostacyclin receptor, Prostaglandin I2 receptor, PGI receptor, PGI2 receptor, Prostanoid IP receptor, PTGIR, PRIPR |
| Format | Peptides are lyophilized in a solid powder format. Peptides can be reconstituted in solution using the appropriate buffer as needed. |
| Storage | Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C. |
| Precautions | This product is for research use only. Not for use in diagnostic or therapeutic procedures. |
| Name | PTGIR |
|---|---|
| Synonyms | PRIPR |
| Function | Receptor for prostacyclin (prostaglandin I2 or PGI2). The activity of this receptor is mediated by G(s) proteins which activate adenylate cyclase. |
| Cellular Location | Cell membrane; Multi-pass membrane protein. |
Thousands of laboratories across the world have published research that depended on the performance of antibodies from Abcepta to advance their research. Check out links to articles that cite our products in major peer-reviewed journals, organized by research category.
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Provided below are standard protocols that you may find useful for product applications.
Background
The protein encoded by this gene is a member of theG-protein coupled receptor family 1 and has been shown to be areceptor for prostacyclin. Prostacyclin, the major product ofcyclooxygenase in macrovascular endothelium, elicits a potentvasodilation and inhibition of platelet aggregation through bindingto this receptor.
References
Bailey, S.D., et al. Diabetes Care 33(10):2250-2253(2010)Ibrahim, S., et al. Arterioscler. Thromb. Vasc. Biol. 30(9):1802-1809(2010)Reid, H.M., et al. J. Biol. Chem. 285(24):18709-18726(2010)Muto, A., et al. Int Angiol 29 (2 SUPPL), 43-48 (2010) :Davila, S., et al. Genes Immun. 11(3):232-238(2010)
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