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PTGIR Antibody (Center) Blocking Peptide

Synthetic peptide

     
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Product Information
Primary Accession P43119
Clone Names 100525141
Peptide ID 100525141
Additional Information
Gene ID 5739
Other Names Prostacyclin receptor, Prostaglandin I2 receptor, PGI receptor, PGI2 receptor, Prostanoid IP receptor, PTGIR, PRIPR
Format Synthetic peptide was lyophilized with 100% acetonitrile and is supplied as a powder. Reconstitute with 0.1 ml DI water for a final concentration of 1 mg/ml.
StorageMaintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C.
PrecautionsThis product is for research use only. Not for use in diagnostic or therapeutic procedures.
Protein Information
Name PTGIR
Synonyms PRIPR
Function Receptor for prostacyclin (prostaglandin I2 or PGI2). The activity of this receptor is mediated by G(s) proteins which activate adenylate cyclase.
Cellular Location Cell membrane; Multi-pass membrane protein.
Research Areas
Citations (0)

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Background

The protein encoded by this gene is a member of theG-protein coupled receptor family 1 and has been shown to be areceptor for prostacyclin. Prostacyclin, the major product ofcyclooxygenase in macrovascular endothelium, elicits a potentvasodilation and inhibition of platelet aggregation through bindingto this receptor.

References

Bailey, S.D., et al. Diabetes Care 33(10):2250-2253(2010)Ibrahim, S., et al. Arterioscler. Thromb. Vasc. Biol. 30(9):1802-1809(2010)Reid, H.M., et al. J. Biol. Chem. 285(24):18709-18726(2010)Muto, A., et al. Int Angiol 29 (2 SUPPL), 43-48 (2010) :Davila, S., et al. Genes Immun. 11(3):232-238(2010)

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$ 80.00
Cat# BP14427c
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