|Other Names||Prostacyclin receptor, Prostaglandin I2 receptor, PGI receptor, PGI2 receptor, Prostanoid IP receptor, PTGIR, PRIPR|
|Format||Synthetic peptide was lyophilized with 100% acetonitrile and is supplied as a powder. Reconstitute with 0.1 ml DI water for a final concentration of 1 mg/ml.|
|Storage||Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C.|
|Precautions||This product is for research use only. Not for use in diagnostic or therapeutic procedures.|
|Function||Receptor for prostacyclin (prostaglandin I2 or PGI2). The activity of this receptor is mediated by G(s) proteins which activate adenylate cyclase.|
|Cellular Location||Cell membrane; Multi-pass membrane protein.|
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Provided below are standard protocols that you may find useful for product applications.
The protein encoded by this gene is a member of theG-protein coupled receptor family 1 and has been shown to be areceptor for prostacyclin. Prostacyclin, the major product ofcyclooxygenase in macrovascular endothelium, elicits a potentvasodilation and inhibition of platelet aggregation through bindingto this receptor.
Bailey, S.D., et al. Diabetes Care 33(10):2250-2253(2010)Ibrahim, S., et al. Arterioscler. Thromb. Vasc. Biol. 30(9):1802-1809(2010)Reid, H.M., et al. J. Biol. Chem. 285(24):18709-18726(2010)Muto, A., et al. Int Angiol 29 (2 SUPPL), 43-48 (2010) :Davila, S., et al. Genes Immun. 11(3):232-238(2010)
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