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TBX21 Antibody (N-term) Blocking Peptide

Synthetic peptide

Product Information
Primary Accession Q9UL17
Clone Names 100525142
Peptide ID 100525142
Additional Information
Gene ID 30009
Other Names T-box transcription factor TBX21, T-box protein 21, T-cell-specific T-box transcription factor T-bet, Transcription factor TBLYM, TBX21, TBET, TBLYM
Format Synthetic peptide was lyophilized with 100% acetonitrile and is supplied as a powder. Reconstitute with 0.1 ml DI water for a final concentration of 1 mg/ml.
StorageMaintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C.
PrecautionsThis product is for research use only. Not for use in diagnostic or therapeutic procedures.
Protein Information
Name TBX21
Synonyms TBET, TBLYM
Function Transcription factor that controls the expression of the TH1 cytokine, interferon-gamma. Initiates TH1 lineage development from naive TH precursor cells both by activating TH1 genetic programs and by repressing the opposing TH2 programs.
Cellular Location Nucleus.
Tissue Location T-cell specific.
Research Areas
Citations (0)

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This gene is a member of a phylogenetically conservedfamily of genes that share a common DNA-binding domain, the T-box.T-box genes encode transcription factors involved in the regulationof developmental processes. This gene is the human ortholog ofmouse Tbx21/Tbet gene. Studies in mouse show that Tbx21 protein isa Th1 cell-specific transcription factor that controls theexpression of the hallmark Th1 cytokine, interferon-gamma (IFNG).Expression of the human ortholog also correlates with IFNGexpression in Th1 and natural killer cells, suggesting a role forthis gene in initiating Th1 lineage development from naive Thprecursor cells.


Mohr, E., et al. Proc. Natl. Acad. Sci. U.S.A. 107(40):17292-17297(2010)Zhu, Y., et al. J. Immunol. 185(6):3174-3183(2010)Qu, Y., et al. J. Immunol. 185(5):2895-2902(2010)Schuurhof, A., et al. Pediatr. Pulmonol. 45(6):608-613(2010)Jugessur, A., et al. PLoS ONE 5 (7), E11493 (2010) :

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$ 80.00
Cat# BP14428a
(40 western blots)
Availability: In Stock
Bulk Size
Seasonal Special on Bulk Order
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