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>   home   >   Products   >   Peptides   >   Blocking Peptides   >   Stanniocalcin-2 (STC2) Antibody (N-term) Blocking peptide   

Stanniocalcin-2 (STC2) Antibody (N-term) Blocking peptide

Synthetic peptide

Product Information
Primary Accession O76061
Clone Names 70319156
Peptide ID 70319156
Additional Information
Gene ID 8614
Other Names Stanniocalcin-2, STC-2, Stanniocalcin-related protein, STC-related protein, STCRP, STC2
Target/Specificity The synthetic peptide sequence used to generate the antibody AP1443a was selected from the N-term region of human STC2. A 10 to 100 fold molar excess to antibody is recommended. Precise conditions should be optimized for a particular assay.
Format The synthetic peptide was lyophilized with 100% acetonitrile and is supplied as a powder. Reconstitute with 0.1 ml deionized water for a final concentration of 1 mg/ml.
StorageMaintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C.
PrecautionsThis product is for research use only. Not for use in diagnostic or therapeutic procedures.
Protein Information
Name STC2
Function Has an anti-hypocalcemic action on calcium and phosphate homeostasis.
Cellular Location Secreted.
Tissue Location Expressed in a variety of tissues including muscle, heart, pancreas, kidney, spleen, prostate, small intestine, colon and peripheral blood leukocytes
Research Areas
Citations (0)

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STC2 is a secreted, homodimeric glycoprotein that is expressed in a wide variety of tissues and may have autocrine or paracrine functions. The encoded protein has 10 of its 15 cysteine residues conserved among stanniocalcin family members and is phosphorylated by casein kinase 2 exclusively on its serine residues. Its C-terminus contains a cluster of histidine residues which may interact with metal ions. The protein may play a role in the regulation of renal and intestinal calcium and phosphate transport, cell metabolism, or cellular calcium/phosphate homeostasis. Constitutive overexpression of human stanniocalcin 2 in mice resulted in pre- and postnatal growth restriction, reduced bone and skeletal muscle growth, and organomegaly. Expression is induced by estrogen and altered in some breast cancers.


Ishibashi, K., et al., Biochem. Biophys. Res. Commun. 250(2):252-258 (1998).DiMattia, G.E., et al., Mol. Cell. Endocrinol. 146 (1-2), 137-140 (1998).Chang, A.C., et al., Mol. Cell. Endocrinol. 141 (1-2), 95-99 (1998).

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$ 80.00
Cat# BP1443a
(40 western blots)
Availability: In Stock
Bulk Size
Seasonal Special on Bulk Order
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