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ALDH1A1 Antibody (N-term) Blocking PeptideSynthetic peptide
| Country | United States
Ordering Information
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|---|---|---|---|---|
| Catalog # | Size | Availability | Price | |
| BP1445a | 0.1 mg 400 ul | In Stock | $ 45.00 | DISCONTINED INQUIRE CLICK INQUIRE Add to cart |
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ALDH1A1 Antibody (N-term) Blocking Peptide - Product info | |
| Primary Accession | P00352 |
| Clone Names | 70319182 |
| Calculated MW | 54862 Da |
ALDH1A1 Antibody (N-term) Blocking Peptide - Additional info | |
| Gene ID 216 | |
| Target/Specificity The synthetic peptide sequence used to generate the antibody AP1445a was selected from the N-term region of human ALDH1A1. A 10 to 100 fold molar excess to antibody is recommended. Precise conditions should be optimized for a particular assay. | |
| Format The synthetic peptide was lyophilized with 100% acetonitrile and is supplied as a powder. Reconstitute with 0.1 ml deionized water for a final concentration of 1 mg/ml. | |
| Storage Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C. | |
| Precautions This product is for research use only. Not for use in diagnostic or therapeutic procedures. | |
ALDH1A1 Antibody (N-term) Blocking Peptide - Protein Information | |
| Name ALDH1A1 | |
| Synonyms ALDC, ALDH1, PUMB1 | |
| Function Binds free retinal and cellular retinol-binding protein- bound retinal. Can convert/oxidize retinaldehyde to retinoic acid (By similarity) | |
| Cellular Location Cytoplasm. | |
ALDH1A1 Antibody (N-term) Blocking Peptide - Related products
AM1846a: ALDH1A1 Antibody (Ascites)
AP1445a: ALDH1A1 Antibody (N-term)
AP1465c: ALDH1A1 Antibody (Center)
RI10225: ALDH1A1 predesign siRNA
LY12320a: AL1A1 Over-expression Lysate
BP1445a: ALDH1A1 Antibody (N-term) Blocking Peptide
BP1465c: ALDH1A1 Antibody (Center) Blocking Peptide
ALDH1A1 Antibody (N-term) Blocking Peptide - Research Areas
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BACKGROUND
This protein belongs to the aldehyde dehydrogenases family of proteins. Aldehyde dehydrogenase is the second enzyme of the major oxidative pathway of alcohol metabolism. Two major liver isoforms of this enzyme, cytosolic and mitochondrial, can be distinguished by their electrophoretic mobilities, kinetic properties, and subcellular localizations. Most Caucasians have twomajor isozymes, while approximately 50% of Orientals have only the cytosolic isozyme, missing the mitochondrial isozyme. A remarkably higher frequency of acute alcohol intoxication among Orientals than among Caucasians could be related to the absence of the mitochondrial isozyme. ALDH1A1 is a cytosolic isoform, which has a high affinity for aldehydes.