Mouse Styk1 Antibody (Center) Blocking Peptide
Synthetic peptide
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
Primary Accession | Q6J9G1 |
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Clone Names | 110328114 |
Gene ID | 243659 |
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Other Names | Tyrosine-protein kinase STYK1, Novel oncogene with kinase domain, mNOK, Serine/threonine/tyrosine kinase 1, Styk1, Nok |
Format | Peptides are lyophilized in a solid powder format. Peptides can be reconstituted in solution using the appropriate buffer as needed. |
Storage | Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C. |
Precautions | This product is for research use only. Not for use in diagnostic or therapeutic procedures. |
Name | Styk1 |
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Synonyms | Nok |
Function | Probable tyrosine protein-kinase, which has strong transforming capabilities on a variety of cell lines including NIH 3T3 fibroblasts and on athymic nude mice. When overexpressed, it can also induce tumor cell invasion as well as metastasis in distant organs. May act by activating both MAP kinase and phosphatidylinositol 3'-kinases (PI3K) pathways. |
Cellular Location | Membrane; Single-pass membrane protein |
Tissue Location | Highly expressed in colon and small intestine. Weakly or not expressed in spleen, skeletal muscle, liver, kidney, heart and brain. Expressed in transformed kidney cell lines (COS-1 and HEK293T). |
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Provided below are standard protocols that you may find useful for product applications.
Background
Probable tyrosine protein-kinase, which has strong transforming capabilities on a variety of cell lines including NIH 3T3 fibroblasts and on athymic nude mice. When overexpressed, it can also induce tumor cell invasion as well as metastasis in distant organs. May act by activating both MAP kinase and phosphatidylinositol 3'-kinases (PI3K) pathways.
References
Chen, Y., et al. Cancer Res. 65(23):10838-10846(2005)Liu, L., et al. Cancer Res. 64(10):3491-3499(2004)
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