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AKR1C1 Antibody (C-term) Blocking Peptide

Synthetic peptide

Product Information
Primary Accession Q04828
Clone Names 100311226
Peptide ID 100311226
Additional Information
Gene ID 1645
Other Names Aldo-keto reductase family 1 member C1, 111-, 20-alpha-hydroxysteroid dehydrogenase, 20-alpha-HSD, Chlordecone reductase homolog HAKRC, Dihydrodiol dehydrogenase 1/2, DD1/DD2, High-affinity hepatic bile acid-binding protein, HBAB, Indanol dehydrogenase, Trans-1, 2-dihydrobenzene-1, 2-diol dehydrogenase, AKR1C1, DDH, DDH1
Format Synthetic peptide was lyophilized with 100% acetonitrile and is supplied as a powder. Reconstitute with 0.1 ml DI water for a final concentration of 1 mg/ml.
StorageMaintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C.
PrecautionsThis product is for research use only. Not for use in diagnostic or therapeutic procedures.
Protein Information
Name AKR1C1
Synonyms DDH, DDH1
Function Converts progesterone to its inactive form, 20-alpha- dihydroxyprogesterone (20-alpha-OHP). In the liver and intestine, may have a role in the transport of bile. May have a role in monitoring the intrahepatic bile acid concentration. Has a low bile-binding ability. May play a role in myelin formation.
Cellular Location Cytoplasm.
Tissue Location Expressed in all tissues tested including liver, prostate, testis, adrenal gland, brain, uterus, mammary gland and keratinocytes. Highest levels found in liver, mammary gland and brain.
Research Areas
Citations (0)

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This gene encodes a member of the aldo/keto reductasesuperfamily, which consists of more than 40 known enzymes andproteins. These enzymes catalyze the conversion of aldehydes andketones to their corresponding alcohols by utilizing NADH and/orNADPH as cofactors. The enzymes display overlapping but distinctsubstrate specificity. This enzyme catalyzes the reaction ofprogesterone to the inactive form 20-alpha-hydroxy-progesterone.This gene shares high sequence identity with three other genemembers and is clustered with those three genes at chromosome10p15-p14.


Joslyn, G., et al. Alcohol. Clin. Exp. Res. 34(5):800-812(2010)Wang, X., et al. PLoS ONE 5 (8), E11934 (2010) :Reding, K.W., et al. Am. J. Epidemiol. 170(10):1241-1249(2009)Chien, C.W., et al. Carcinogenesis 30(10):1813-1820(2009)Davies, N.J., et al. Cancer Res. 69(11):4769-4775(2009)

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$ 80.00
Cat# BP14485b
(40 western blots)
Availability: In Stock
Bulk Size
Seasonal Special on Bulk Order
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