|Other Names||Myosin light chain 3, Cardiac myosin light chain 1, CMLC1, Myosin light chain 1, slow-twitch muscle B/ventricular isoform, MLC1SB, Ventricular/slow twitch myosin alkali light chain, MYL3|
|Format||Synthetic peptide was lyophilized with 100% acetonitrile and is supplied as a powder. Reconstitute with 0.1 ml DI water for a final concentration of 1 mg/ml.|
|Storage||Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C.|
|Precautions||This product is for research use only. Not for use in diagnostic or therapeutic procedures.|
|Function||Regulatory light chain of myosin. Does not bind calcium.|
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Provided below are standard protocols that you may find useful for product applications.
MYL3 encodes myosin light chain 3, an alkali light chainalso referred to in the literature as both the ventricular isoformand the slow skeletal muscle isoform. Mutations in MYL3 have beenidentified as a cause of mid-left ventricular chamber typehypertrophic cardiomyopathy.
Bailey, S.D., et al. Diabetes Care 33(10):2250-2253(2010)Girolami, F., et al. J. Am. Coll. Cardiol. 55(14):1444-1453(2010)Talmud, P.J., et al. Am. J. Hum. Genet. 85(5):628-642(2009)McLeod, C.J., et al. Am. Heart J. 158(5):799-805(2009)Kaski, J.P., et al. Circ Cardiovasc Genet 2(5):436-441(2009)
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