ETV6 Antibody (Center) Blocking Peptide
Synthetic peptide
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
Primary Accession | P41212 |
---|---|
Clone Names | 100430244 |
Gene ID | 2120 |
---|---|
Other Names | Transcription factor ETV6, ETS translocation variant 6, ETS-related protein Tel1, Tel, ETV6, TEL, TEL1 |
Format | Peptides are lyophilized in a solid powder format. Peptides can be reconstituted in solution using the appropriate buffer as needed. |
Storage | Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C. |
Precautions | This product is for research use only. Not for use in diagnostic or therapeutic procedures. |
Name | ETV6 |
---|---|
Synonyms | TEL, TEL1 |
Function | Transcriptional repressor; binds to the DNA sequence 5'- CCGGAAGT-3'. Plays a role in hematopoiesis and malignant transformation. |
Cellular Location | Nucleus. |
Tissue Location | Ubiquitous. |
Thousands of laboratories across the world have published research that depended on the performance of antibodies from Abcepta to advance their research. Check out links to articles that cite our products in major peer-reviewed journals, organized by research category.
info@abcepta.com, and receive a free "I Love Antibodies" mug.
Provided below are standard protocols that you may find useful for product applications.
Background
This gene encodes an ETS family transcription factor. Theproduct of this gene contains two functional domains: a N-terminalpointed (PNT) domain that is involved in protein-proteininteractions with itself and other proteins, and a C-terminalDNA-binding domain. Gene knockout studies in mice suggest that itis required for hematopoiesis and maintenance of the developingvascular network. This gene is known to be involved in a largenumber of chromosomal rearrangements associated with leukemia andcongenital fibrosarcoma.
References
Otsubo, K., et al. Cancer Genet. Cytogenet. 202(1):22-26(2010)Roukens, M.G., et al. Nat. Cell Biol. 12(10):933-942(2010)Bailey, S.D., et al. Diabetes Care 33(10):2250-2253(2010)Gascon, E., et al. J. Neurosci. 30(37):12414-12423(2010)Liang, D.C., et al. Pediatr Blood Cancer 55(3):430-433(2010)
If you have used an Abcepta product and would like to share how it has performed, please click on the "Submit Review" button and provide the requested information. Our staff will examine and post your review and contact you if needed.
If you have any additional inquiries please email technical services at tech@abcepta.com.