|Other Names||GTP-binding protein Rit1, Ras-like protein expressed in many tissues, Ras-like without CAAX protein 1, RIT1, RIBB, RIT, ROC1|
|Format||Synthetic peptide was lyophilized with 100% acetonitrile and is supplied as a powder. Reconstitute with 0.1 ml DI water for a final concentration of 1 mg/ml.|
|Storage||Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C.|
|Precautions||This product is for research use only. Not for use in diagnostic or therapeutic procedures.|
|Synonyms||RIBB, RIT, ROC1|
|Function||Plays a crucial role in coupling NGF stimulation to the activation of both EPHB2 and MAPK14 signaling pathways and in NGF- dependent neuronal differentiation. Involved in ELK1 transactivation through the Ras-MAPK signaling cascade that mediates a wide variety of cellular functions, including cell proliferation, survival, and differentiation.|
|Cellular Location||Cell membrane.|
|Tissue Location||Expressed in many tissues.|
Thousands of laboratories across the world have published research that depended on the performance of antibodies from Abgent to advance their research. Check out links to articles that cite our products in major peer-reviewed journals, organized by research category.
firstname.lastname@example.org, and receive a free "I Love Antibodies" mug.
Provided below are standard protocols that you may find useful for product applications.
RIT belongs to the RAS (HRAS; MIM 190020) subfamily ofsmall GTPases (Hynds et al., 2003 [PubMed 12668729]).[supplied byOMIM].
Lee, Y.R., et al. EMBO J. 29(10):1748-1761(2010)Katiyar, S., et al. EMBO Rep. 10(8):866-872(2009)Sonuga-Barke, E.J., et al. Am. J. Med. Genet. B Neuropsychiatr. Genet. 147B (8), 1359-1368 (2008) :Hu, J., et al. Genes Dev. 22(7):866-871(2008)Wu, C., et al. Proteomics 7(11):1775-1785(2007)
If you have used an Abgent product and would like to share how it has performed, please click on the "Submit Review" button and provide the requested information. Our staff will examine and post your review and contact you if needed.
If you have any additional inquiries please email technical services at email@example.com.