|Other Names||Pre-mRNA-splicing factor SPF27, Breast carcinoma-amplified sequence 2, DNA amplified in mammary carcinoma 1 protein, Spliceosome-associated protein SPF 27, BCAS2, DAM1|
|Format||Synthetic peptide was lyophilized with 100% acetonitrile and is supplied as a powder. Reconstitute with 0.1 ml DI water for a final concentration of 1 mg/ml.|
|Storage||Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C.|
|Precautions||This product is for research use only. Not for use in diagnostic or therapeutic procedures.|
|Function||Component of the PRP19-CDC5L complex that forms an integral part of the spliceosome and is required for activating pre-mRNA splicing. May have a scaffolding role in the spliceosome assembly as it contacts all other components of the core complex. The PRP19-CDC5L complex may also play a role in the response to DNA damage (DDR).|
|Cellular Location||Nucleus, nucleolus|
|Tissue Location||Ubiquitously expressed.|
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Provided below are standard protocols that you may find useful for product applications.
BCAS2 is involved in mRNA splicing (By similarity).
Kuo, P.C., et al. Cancer Res. 69(23):8877-8885(2009)Ewing, R.M., et al. Mol. Syst. Biol. 3, 89 (2007) :Qi, C., et al. Biochem. Biophys. Res. Commun. 328(2):393-398(2005)Lee, S., et al. Cancer Lett. 188 (1-2), 121-126 (2002) :Maass, N., et al. Cancer Lett. 185(2):219-223(2002)
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