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BCAS2 Antibody (N-term) Blocking Peptide

Synthetic peptide

     
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Product Information
Primary Accession O75934
Clone Names 100517165
Additional Information
Gene ID 10286
Other Names Pre-mRNA-splicing factor SPF27, Breast carcinoma-amplified sequence 2, DNA amplified in mammary carcinoma 1 protein, Spliceosome-associated protein SPF 27, BCAS2, DAM1
Format Peptides are lyophilized in a solid powder format. Peptides can be reconstituted in solution using the appropriate buffer as needed.
StorageMaintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C.
PrecautionsThis product is for research use only. Not for use in diagnostic or therapeutic procedures.
Protein Information
Name BCAS2
Synonyms DAM1 {ECO:0000303|PubMed:10403562}
Function Required for pre-mRNA splicing as component of the activated spliceosome (PubMed:28502770, PubMed:28076346, PubMed:29360106, PubMed:29301961, PubMed:30705154). Component of the PRP19-CDC5L complex that forms an integral part of the spliceosome and is required for activating pre-mRNA splicing. May have a scaffolding role in the spliceosome assembly as it contacts all other components of the core complex. The PRP19-CDC5L complex may also play a role in the response to DNA damage (DDR).
Cellular Location Nucleus. Nucleus, nucleolus
Tissue Location Ubiquitously expressed.
Research Areas
Citations (0)
citation

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Background

BCAS2 is involved in mRNA splicing (By similarity).

References

Kuo, P.C., et al. Cancer Res. 69(23):8877-8885(2009)Ewing, R.M., et al. Mol. Syst. Biol. 3, 89 (2007) :Qi, C., et al. Biochem. Biophys. Res. Commun. 328(2):393-398(2005)Lee, S., et al. Cancer Lett. 188 (1-2), 121-126 (2002) :Maass, N., et al. Cancer Lett. 185(2):219-223(2002)

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$ 277.78
Cat# BP14509a
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