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GPR27 Antibody (Center) Blocking Peptide
Synthetic peptide
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
| Primary Accession | Q9NS67 |
|---|---|
| Clone Names | 100517283 |
| Gene ID | 2850 |
|---|---|
| Other Names | Probable G-protein coupled receptor 27, Super conserved receptor expressed in brain 1, GPR27, SREB1 |
| Format | Peptides are lyophilized in a solid powder format. Peptides can be reconstituted in solution using the appropriate buffer as needed. |
| Storage | Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C. |
| Precautions | This product is for research use only. Not for use in diagnostic or therapeutic procedures. |
| Name | GPR27 |
|---|---|
| Synonyms | SREB1 |
| Function | Orphan receptor. Possible candidate for amine-like G-protein coupled receptor. |
| Cellular Location | Cell membrane; Multi-pass membrane protein |
| Tissue Location | Highly expressed as a 3.0 kb transcript in brain, ovary, testis, heart, prostate and peripheral Leukocytes. Lower levels in pancreas and small intestine. A 2.3 kb transcript was also found in peripheral Leukocytes. In brain regions, detected as a 3.0 kb transcript in all regions tested. Highest levels in the caudate nucleus, putamen, hippocampus and subthalamic nucleus. Lowest level in the cerebellum |
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Provided below are standard protocols that you may find useful for product applications.
Background
GPR27 is a member of the G protein-coupled receptors(GPCRs), a large family of receptors that have a similar structurecharacterized by 7 transmembrane domains. Activation of GPCRs byextracellular stimuli such as neurotransmitters, hormones, or lightinduces an intracellular signaling cascade mediated byheterotrimeric GTP-binding proteins, or G proteins.[supplied byOMIM].
References
Matsumoto, M., et al. Biochem. Biophys. Res. Commun. 272(2):576-582(2000)
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