|Other Names||Probable G-protein coupled receptor 27, Super conserved receptor expressed in brain 1, GPR27, SREB1|
|Format||Synthetic peptide was lyophilized with 100% acetonitrile and is supplied as a powder. Reconstitute with 0.1 ml DI water for a final concentration of 1 mg/ml.|
|Storage||Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C.|
|Precautions||This product is for research use only. Not for use in diagnostic or therapeutic procedures.|
|Function||Orphan receptor. Possible candidate for amine-like G- protein coupled receptor.|
|Cellular Location||Cell membrane; Multi-pass membrane protein|
|Tissue Location||Highly expressed as a 3.0 kb transcript in brain, ovary, testis, heart, prostate and peripheral Leukocytes Lower levels in pancreas and small intestine. A 2.3 kb transcript was also found in peripheral Leukocytes. In brain regions, detected as a 3.0 kb transcript in all regions tested. Highest levels in the caudate nucleus, putamen, hippocampus and subthalamic nucleus. Lowest level in the cerebellum|
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Provided below are standard protocols that you may find useful for product applications.
GPR27 is a member of the G protein-coupled receptors(GPCRs), a large family of receptors that have a similar structurecharacterized by 7 transmembrane domains. Activation of GPCRs byextracellular stimuli such as neurotransmitters, hormones, or lightinduces an intracellular signaling cascade mediated byheterotrimeric GTP-binding proteins, or G proteins.[supplied byOMIM].
Matsumoto, M., et al. Biochem. Biophys. Res. Commun. 272(2):576-582(2000)
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