Foundational characteristics of cancer include proliferation, angiogenesis, migration, evasion of apoptosis, and cellular immortality. Find key markers for these cellular processes and antibodies to detect them.
The SUMOplot™ Analysis Program predicts and scores sumoylation sites in your protein. SUMOylation is a post-translational modification involved in various cellular processes, such as nuclear-cytosolic transport, transcriptional regulation, apoptosis, protein stability, response to stress, and progression through the cell cycle.
The Autophagy Receptor Motif Plotter predicts and scores autophagy receptor binding sites in your protein. Identifying proteins connected to this pathway is critical to understanding the role of autophagy in physiological as well as pathological processes such as development, differentiation, neurodegenerative diseases, stress, infection, and cancer.
PPT2 Antibody (Center) Blocking Peptide
Synthetic peptide
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
| Primary Accession | Q9UMR5 |
|---|---|
| Clone Names | 100517326 |
| Gene ID | 9374 |
|---|---|
| Other Names | Lysosomal thioesterase PPT2, PPT-2, 312-, S-thioesterase G14, PPT2 |
| Format | Peptides are lyophilized in a solid powder format. Peptides can be reconstituted in solution using the appropriate buffer as needed. |
| Storage | Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C. |
| Precautions | This product is for research use only. Not for use in diagnostic or therapeutic procedures. |
| Name | PPT2 |
|---|---|
| Function | Removes thioester-linked fatty acyl groups from various substrates including S-palmitoyl-CoA. Has the highest S-thioesterase activity for the acyl groups palmitic and myristic acid followed by other short- and long-chain acyl substrates. However, because of structural constraints, is unable to remove palmitate from peptides or proteins. |
| Cellular Location | Lysosome. |
| Tissue Location | Broadly expressed, with highest levels in skeletal muscle. |
Thousands of laboratories across the world have published research that depended on the performance of antibodies from Abcepta to advance their research. Check out links to articles that cite our products in major peer-reviewed journals, organized by research category.
info@abcepta.com, and receive a free "I Love Antibodies" mug.
Provided below are standard protocols that you may find useful for product applications.
Background
This gene encodes a member of the palmitoyl-proteinthioesterase family. The encoded glycosylated lysosomal protein haspalmitoyl-CoA hydrolase activity in vitro, but does not hydrolyzepalmitate from cysteine residues in proteins. Three transcriptvariants encoding different isoforms have been described for thisgene, with one of the isoforms being inactive. [provided byRefSeq].
References
Hancock, D.B., et al. Nat. Genet. 42(1):45-52(2010)Barcellos, L.F., et al. PLoS Genet. 5 (10), E1000696 (2009) :McKinnon, E., et al. Diabetes Obes Metab 11 SUPPL 1, 92-100 (2009) :Lamesch, P., et al. Genomics 89(3):307-315(2007)Sleat, D.E., et al. Mol. Cell Proteomics 5(4):686-701(2006)
If you have used an Abcepta product and would like to share how it has performed, please click on the "Submit Review" button and provide the requested information. Our staff will examine and post your review and contact you if needed.
If you have any additional inquiries please email technical services at tech@abcepta.com.
Ordering Information
Other Products
Shipping Information
