|Other Names||SLC2A4 regulator, GLUT4 enhancer factor, GEF, Huntington disease gene regulatory region-binding protein 1, HDBP-1, SLC2A4RG, HDBP1|
|Format||Synthetic peptide was lyophilized with 100% acetonitrile and is supplied as a powder. Reconstitute with 0.1 ml DI water for a final concentration of 1 mg/ml.|
|Storage||Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C.|
|Precautions||This product is for research use only. Not for use in diagnostic or therapeutic procedures.|
|Function||Transcription factor involved in SLC2A4 and HD gene transactivation. Binds to the consensus sequence 5'-GCCGGCG-3'.|
|Cellular Location||Cytoplasm. Nucleus. Note=Shuttles between the cytoplasm and the nucleus|
|Tissue Location||According to PubMed:14630949, expressed in heart, skeletal muscle, liver, kidney and pancreas; undetectable in lung, placenta or brain. According to PubMed:14625278, ubiquitously expressed, with lowest expression in brain and ileum|
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Provided below are standard protocols that you may find useful for product applications.
The protein encoded by this gene is a nucleartranscription factor involved in the activation of the solutecarrier family 2 member 4 gene. The encoded protein interacts withanother transcription factor, myocyte enhancer factor 2, toactivate transcription of this gene.
Jones, M.R., et al. Fertil. Steril. 90(6):2298-2303(2008)McGee, S.L., et al. FASEB J. 20(2):348-349(2006)Tanaka, K., et al. J. Biol. Chem. 279(8):7275-7286(2004)Knight, J.B., et al. Proc. Natl. Acad. Sci. U.S.A. 100(25):14725-14730(2003)Deloukas, P., et al. Nature 414(6866):865-871(2001)
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