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OSM Antibody (C-term) Blocking Peptide
Synthetic peptide
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
| Primary Accession | P13725 |
|---|---|
| Clone Names | 100525114 |
| Gene ID | 5008 |
|---|---|
| Other Names | Oncostatin-M, OSM, OSM |
| Format | Peptides are lyophilized in a solid powder format. Peptides can be reconstituted in solution using the appropriate buffer as needed. |
| Storage | Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C. |
| Precautions | This product is for research use only. Not for use in diagnostic or therapeutic procedures. |
| Name | OSM |
|---|---|
| Function | Growth regulator. Inhibits the proliferation of a number of tumor cell lines. Stimulates proliferation of AIDS-KS cells. It regulates cytokine production, including IL-6, G-CSF and GM-CSF from endothelial cells. Uses both type I OSM receptor (heterodimers composed of LIFR and IL6ST) and type II OSM receptor (heterodimers composed of OSMR and IL6ST). Involved in the maturation of fetal hepatocytes, thereby promoting liver development and regeneration (By similarity). |
| Cellular Location | Secreted. |
Thousands of laboratories across the world have published research that depended on the performance of antibodies from Abcepta to advance their research. Check out links to articles that cite our products in major peer-reviewed journals, organized by research category.
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Provided below are standard protocols that you may find useful for product applications.
Background
Oncostatin M is a member of a cytokine family thatincludes leukemia-inhibitory factor, granulocyte colony-stimulatingfactor, and interleukin 6. This gene encodes a growth regulatorwhich inhibits the proliferation of a number of tumor cell lines.It regulates cytokine production, including IL-6, G-CSF and GM-CSFfrom endothelial cells.
References
Bailey, S.D., et al. Diabetes Care 33(10):2250-2253(2010)Thorat Manojkumar, S., et al. Cytokine 50(3):248-252(2010)Pradeep, A.R., et al. Biomarkers 15(3):277-282(2010)Davila, S., et al. Genes Immun. 11(3):232-238(2010)Lee, G., et al. J. Obstet. Gynaecol. Res. 35(5):869-875(2009)
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