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NRF1 Antibody (Center) Blocking Peptide

Synthetic peptide

Product Information
Primary Accession Q16656
Clone Names 100525164
Peptide ID 100525164
Additional Information
Gene ID 4899
Other Names Nuclear respiratory factor 1, NRF-1, Alpha palindromic-binding protein, Alpha-pal, NRF1
Format Synthetic peptide was lyophilized with 100% acetonitrile and is supplied as a powder. Reconstitute with 0.1 ml DI water for a final concentration of 1 mg/ml.
StorageMaintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C.
PrecautionsThis product is for research use only. Not for use in diagnostic or therapeutic procedures.
Protein Information
Name NRF1
Function Transcription factor that activates the expression of the EIF2S1 (EIF2-alpha) gene. Links the transcriptional modulation of key metabolic genes to cellular growth and development. Implicated in the control of nuclear genes required for respiration, heme biosynthesis, and mitochondrial DNA transcription and replication.
Cellular Location Nucleus.
Tissue Location Ubiquitously expressed with strongest expression in skeletal muscle
Research Areas
Citations (0)

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This gene encodes a protein that homodimerizes andfunctions as a transcription factor which activates the expressionof some key metabolic genes regulating cellular growth and nucleargenes required for respiration, heme biosynthesis, andmitochondrial DNA transcription and replication. The protein hasalso been associated with the regulation of neurite outgrowth.Alternate transcriptional splice variants, which encode the sameprotein, have been characterized. Additional variants encodingdifferent protein isoforms have been described but they have notbeen fully characterized. Confusion has occurred in bibliographicdatabases due to the shared symbol of NRF1 for this gene and for'nuclear factor (erythroid-derived 2)-like 1' which has an officialsymbol of NFE2L1.


Gonen, N., et al. J. Biol. Chem. 285(44):33602-33613(2010)Zhang, Y., et al. Biochem. J. 430(3):497-510(2010)Shao, D., et al. Mitochondrion 10(5):516-527(2010)Adam, T., et al. Biochem. Biophys. Res. Commun. 398(3):495-499(2010)Spelbrink, J.N., et al. Hum. Mol. Genet. 4(9):1591-1596(1995)

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$ 80.00
Cat# BP14535c
Availability: In Stock
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