Register or Login
  • All
  • Uniprot Id
  • Catalog #
  • Peptide Sequence
>   home   >   Products   >   Peptides   >   Blocking Peptides   >   NXF1 Antibody (N-term) Blocking Peptide   

NXF1 Antibody (N-term) Blocking Peptide

Synthetic peptide

Product Information
Primary Accession Q9UBU9
Clone Names 100525174
Peptide ID 100525174
Additional Information
Gene ID 10482
Other Names Nuclear RNA export factor 1, Tip-associated protein, Tip-associating protein, mRNA export factor TAP, NXF1, TAP
Format Synthetic peptide was lyophilized with 100% acetonitrile and is supplied as a powder. Reconstitute with 0.1 ml DI water for a final concentration of 1 mg/ml.
StorageMaintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C.
PrecautionsThis product is for research use only. Not for use in diagnostic or therapeutic procedures.
Protein Information
Name NXF1
Synonyms TAP
Function Involved in the nuclear export of mRNA species bearing retroviral constitutive transport elements (CTE) and in the export of mRNA from the nucleus to the cytoplasm (TAP/NFX1 pathway). The NXF1-NXT1 heterodimer is involved in the export of HSP70 mRNA in conjunction with ALYREF/THOC4 and THOC5 components of the TREX complex. ALYREF/THOC4-bound mRNA is thought to be transferred to the NXF1-NXT1 heterodimer for export.
Cellular Location Nucleus, nucleoplasm. Nucleus speckle. Cytoplasm. Note=Localized predominantly in the nucleoplasm and at both the nucleoplasmic and cytoplasmic faces of the nuclear pore complex. Shuttles between the nucleus and the cytoplasm. Travels to the cytoplasm as part of the exon junction complex (EJC) bound to mRNA. The association with the TREX complex seems to occur in regions surrounding nuclear speckles known as perispeckles
Tissue Location Expressed ubiquitously.
Research Areas
Citations (0)

Thousands of laboratories across the world have published research that depended on the performance of antibodies from Abgent to advance their research. Check out links to articles that cite our products in major peer-reviewed journals, organized by research category.

Submit your citation using an Abgent antibody to, and receive a free "I Love Antibodies" mug.


This gene is one member of a family of nuclear RNA exportfactor genes. Common domain features of this family are anoncanonical RNP-type RNA-binding domain (RBD), 4 leucine-richrepeats (LRRs), a nuclear transport factor 2 (NTF2)-like domainthat allows heterodimerization with NTF2-related export protein-1(NXT1), and a ubiquitin-associated domain that mediatesinteractions with nucleoporins. The LRRs and NTF2-like domains arerequired for export activity. Alternative splicing seems to be acommon mechanism in this gene family. The encoded protein of thisgene shuttles between the nucleus and the cytoplasm and binds invivo to poly(A)+ RNA. It is the vertebrate homologue of the yeastprotein Mex67p. The encoded protein overcomes the mRNA export blockcaused by the presence of saturating amounts of CTE (constitutivetransport element) RNA of type D retroviruses. Alternative splicingresults in multiple transcript variants.


Read, E.K., et al. J. Gen. Virol. 91 (PT 5), 1290-1301 (2010) :Corbin-Lickfett, K.A., et al. J. Virol. 84(5):2212-2222(2010)Hautbergue, G.M., et al. Curr. Biol. 19(22):1918-1924(2009)Uranishi, H., et al. J. Biol. Chem. 284(38):26106-26116(2009)Ote, I., et al. PLoS ONE 4 (11), E7882 (2009) :

Abgent welcomes feedback from its customers.

If you have used an Abgent product and would like to share how it has performed, please click on the "Submit Review" button and provide the requested information. Our staff will examine and post your review and contact you if needed.

If you have any additional inquiries please email technical services at

$ 80.00
Cat# BP14539a
(40 western blots)
Availability: In Stock
Bulk Size
Seasonal Special on Bulk Order
Request Quote Here

Ordering Information

United States
AlbaniaAustraliaAustriaBelgiumBosnia & HerzegovinaBrazilBulgariaCanadaChinaCroatiaCyprusCzech RepublicDenmarkEstoniaFinlandFranceGermanyGreeceHong KongHungaryIcelandIndiaIndonesiaIrelandIsraelItalyJapanKoreaLatviaLithuaniaLuxembourgMacedoniaMalaysiaMaltaNetherlandsNew ZealandNorwayPakistanPolandPortugalRomaniaSerbiaSingaporeSlovakiaSloveniaSouth AfricaSpainSwedenSwitzerlandTaiwanTurkeyUnited KingdomUnited StatesVietnamOthers
Abgent, Inc.
(888) 735-7227 / (858) 622-0099
(858) 622-0609

Shipping Information

Domestic orders (in stock items)
Shipped out the same day. Orders placed after 1 PM (PST) will ship out the next business day.
International orders
Contact your local distributors
Santa Cruz Alternative
Terms & Conditions