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PRPF31 Antibody (C-term) Blocking Peptide
Synthetic peptide
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
| Primary Accession | Q8WWY3 |
|---|---|
| Clone Names | 100525180 |
| Gene ID | 26121 |
|---|---|
| Other Names | U4/U6 small nuclear ribonucleoprotein Prp31, Pre-mRNA-processing factor 31, Serologically defined breast cancer antigen NY-BR-99, U4/U6 snRNP 61 kDa protein, Protein 61K, hPrp31, PRPF31, PRP31 |
| Format | Peptides are lyophilized in a solid powder format. Peptides can be reconstituted in solution using the appropriate buffer as needed. |
| Storage | Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C. |
| Precautions | This product is for research use only. Not for use in diagnostic or therapeutic procedures. |
| Name | PRPF31 |
|---|---|
| Synonyms | PRP31 |
| Function | Involved in pre-mRNA splicing as component of the spliceosome (PubMed:11867543, PubMed:28781166). Required for the assembly of the U4/U5/U6 tri-snRNP complex, one of the building blocks of the spliceosome (PubMed:11867543). |
| Cellular Location | Nucleus. Nucleus speckle. Nucleus, Cajal body. Note=Predominantly found in speckles and in Cajal bodies. |
| Tissue Location | Ubiquitously expressed. |
Thousands of laboratories across the world have published research that depended on the performance of antibodies from Abcepta to advance their research. Check out links to articles that cite our products in major peer-reviewed journals, organized by research category.
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Provided below are standard protocols that you may find useful for product applications.
Background
This gene encodes a component of the spliceosome complexand is one of several retinitis pigmentosa-causing genes. When thegene product is added to the spliceosome complex, activationoccurs.
References
Schneider, M., et al. Nat. Struct. Mol. Biol. 17(2):216-221(2010)Bujakowska, K., et al. Invest. Ophthalmol. Vis. Sci. 50(12):5927-5933(2009)Potkin, S.G., et al. PLoS ONE 4 (8), E6501 (2009) :Liu, S., et al. Science 316(5821):115-120(2007)Sullivan, L.S., et al. Invest. Ophthalmol. Vis. Sci. 47(10):4579-4588(2006)
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