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SEMG1 Antibody (N-term) Blocking Peptide

Synthetic peptide

     
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Product Information
Primary Accession P04279
Clone Names 100525181
Peptide ID 100525181
Additional Information
Gene ID 6406
Other Names Semenogelin-1, Semenogelin I, SGI, Alpha-inhibin-92, Alpha-inhibin-31, Seminal basic protein, SEMG1, SEMG
Format Synthetic peptide was lyophilized with 100% acetonitrile and is supplied as a powder. Reconstitute with 0.1 ml DI water for a final concentration of 1 mg/ml.
StorageMaintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C.
PrecautionsThis product is for research use only. Not for use in diagnostic or therapeutic procedures.
Protein Information
Name SEMG1
Synonyms SEMG
Function Predominant protein in semen. It participates in the formation of a gel matrix entrapping the accessory gland secretions and ejaculated spermatozoa. Fragments of semenogelin and/or fragments of the related proteins may contribute to the activation of progressive sperm movements as the gel-forming proteins are fragmented by KLK3/PSA.
Cellular Location Secreted.
Tissue Location Seminal vesicle.
Research Areas
Citations (0)

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Background

The protein encoded by this gene is the predominantprotein in semen. The encoded secreted protein is involved in theformation of a gel matrix that encases ejaculated spermatozoa. Theprostate-specific antigen (PSA) protease processes this proteininto smaller peptides, with each possibly having a separatefunction. The proteolysis process breaks down the gel matrix andallows the spermatozoa to move more freely.

References

Mitra, A., et al. Biol. Reprod. 82(3):489-496(2010)Yoshida, K., et al. Cell Motil. Cytoskeleton 66(2):99-108(2009)Ahmed, S.U., et al. Cytotherapy 11(2):238-244(2009)Edstrom, A.M., et al. J. Immunol. 181(5):3413-3421(2008)Emami, N., et al. J. Biol. Chem. 283(28):19561-19569(2008)

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$ 80.00
Cat# BP14543a
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