|Other Names||Semenogelin-1, Semenogelin I, SGI, Alpha-inhibin-92, Alpha-inhibin-31, Seminal basic protein, SEMG1, SEMG|
|Format||Synthetic peptide was lyophilized with 100% acetonitrile and is supplied as a powder. Reconstitute with 0.1 ml DI water for a final concentration of 1 mg/ml.|
|Storage||Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C.|
|Precautions||This product is for research use only. Not for use in diagnostic or therapeutic procedures.|
|Function||Predominant protein in semen. It participates in the formation of a gel matrix entrapping the accessory gland secretions and ejaculated spermatozoa. Fragments of semenogelin and/or fragments of the related proteins may contribute to the activation of progressive sperm movements as the gel-forming proteins are fragmented by KLK3/PSA.|
|Tissue Location||Seminal vesicle.|
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Provided below are standard protocols that you may find useful for product applications.
The protein encoded by this gene is the predominantprotein in semen. The encoded secreted protein is involved in theformation of a gel matrix that encases ejaculated spermatozoa. Theprostate-specific antigen (PSA) protease processes this proteininto smaller peptides, with each possibly having a separatefunction. The proteolysis process breaks down the gel matrix andallows the spermatozoa to move more freely.
Mitra, A., et al. Biol. Reprod. 82(3):489-496(2010)Yoshida, K., et al. Cell Motil. Cytoskeleton 66(2):99-108(2009)Ahmed, S.U., et al. Cytotherapy 11(2):238-244(2009)Edstrom, A.M., et al. J. Immunol. 181(5):3413-3421(2008)Emami, N., et al. J. Biol. Chem. 283(28):19561-19569(2008)
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