|Other Names||Squalene synthase, SQS, SS, FPP:FPP farnesyltransferase, Farnesyl-diphosphate farnesyltransferase, FDFT1|
|Format||Synthetic peptide was lyophilized with 100% acetonitrile and is supplied as a powder. Reconstitute with 0.1 ml DI water for a final concentration of 1 mg/ml.|
|Storage||Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C.|
|Precautions||This product is for research use only. Not for use in diagnostic or therapeutic procedures.|
|Cellular Location||Endoplasmic reticulum membrane; Multi-pass membrane protein|
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Provided below are standard protocols that you may find useful for product applications.
This gene encodes a membrane-associated enzyme located ata branch point in the mevalonate pathway. The encoded protein isthe first specific enzyme in cholesterol biosynthesis, catalyzingthe dimerization of two molecules of farnesyl diphosphate in atwo-step reaction to form squalene.
Chalasani, N., et al. Gastroenterology 139(5):1567-1576(2010)Bailey, S.D., et al. Diabetes Care 33(10):2250-2253(2010)Kovanen, L., et al. Alcohol Alcohol. 45(4):303-311(2010)Lipkin, S.M., et al. Cancer Prev Res (Phila) 3(5):597-603(2010)Sjoholm, L.K., et al. J Circadian Rhythms 8, 1 (2010) :
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