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PPP6C Antibody (C-term) Blocking Peptide

Synthetic peptide

Product Information
Primary Accession O00743
Clone Names 100507139
Peptide ID 100507139
Additional Information
Gene ID 5537
Other Names Serine/threonine-protein phosphatase 6 catalytic subunit, PP6C, Serine/threonine-protein phosphatase 6 catalytic subunit, N-terminally processed, PPP6C, PPP6
Format Synthetic peptide was lyophilized with 100% acetonitrile and is supplied as a powder. Reconstitute with 0.1 ml DI water for a final concentration of 1 mg/ml.
StorageMaintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C.
PrecautionsThis product is for research use only. Not for use in diagnostic or therapeutic procedures.
Protein Information
Name PPP6C
Synonyms PPP6
Function Catalytic subunit of protein phosphatase 6 (PP6). PP6 is a component of a signaling pathway regulating cell cycle progression in response to IL2 receptor stimulation. N-terminal domain restricts G1 to S phase progression in cancer cells, in part through control of cyclin D1. Downregulates MAP3K7 kinase activation of the IL1 signaling pathway by dephosphorylation of MAP3K7.
Cellular Location Cytoplasm
Tissue Location Ubiquitously expressed in all tissues tested with highest expression levels in testis, heart, kidney, brain, stomach, liver and skeletal muscle and lowest in placenta, lung colon and spleen.
Research Areas
Citations (0)

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This gene encodes the catalytic subunit of proteinphosphatase, a component of a signaling pathway regulating cellcycle progression. Splice variants encoding different proteinisoforms exist. The pseudogene of this gene is located onchromosome X.


Douglas, P., et al. Mol. Cell. Biol. 30(6):1368-1381(2010)Dema, B., et al. Genes Immun. 10(7):659-661(2009)Morales-Johansson, H., et al. PLoS ONE 4 (7), E6331 (2009) :Mi, J., et al. PLoS ONE 4 (2), E4395 (2009) :Stefansson, B., et al. Biochemistry 47(5):1442-1451(2008)

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$ 80.00
Cat# BP14562b
(40 western blots)
Availability: In Stock
Bulk Size
Seasonal Special on Bulk Order
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