|Other Names||Dual specificity protein phosphatase 15, VH1-related member Y, Vaccinia virus VH1-related dual-specific protein phosphatase Y, DUSP15, C20orf57, VHY|
|Format||Synthetic peptide was lyophilized with 100% acetonitrile and is supplied as a powder. Reconstitute with 0.1 ml DI water for a final concentration of 1 mg/ml.|
|Storage||Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C.|
|Precautions||This product is for research use only. Not for use in diagnostic or therapeutic procedures.|
|Function||May dephosphorylate MAPK13, ATF2, ERBB3, PDGFRB and SNX6 (PubMed:22792334).|
|Tissue Location||Highly expressed in testis (PubMed:15138252). Expressed in brain; up-regulated in patients with multiple sclerosis gray matter lesions (PubMed:22792334)|
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Provided below are standard protocols that you may find useful for product applications.
The protein encoded by this gene belongs to thenon-receptor class of the protein-tyrosine phosphatase family. Theencoded protein has both protein-tyrosine phophatase activity andserine/threonine-specific phosphatase activity, and therefore isknown as a dual specificity phosphatase. Three transcript variantsencoding two different isoforms have been found for this gene.
Wu, C., et al. Proteomics 7(11):1775-1785(2007)Lamesch, P., et al. Genomics 89(3):307-315(2007)Yoon, T.S., et al. Proteins 61(3):694-697(2005)Alonso, A., et al. J. Biol. Chem. 279(31):32586-32591(2004)Alonso, A., et al. J. Biol. Chem. 279(31):32586-32591(2004)
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