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RAB23 Blocking Peptide (C-term)

Synthetic peptide

Product Information
Primary Accession Q9ULC3
Additional Information
Gene ID 51715
Other Names Ras-related protein Rab-23, RAB23
Target/Specificity The synthetic peptide sequence is selected from aa 217-231 of HUMAN RAB23
Format Synthetic peptide was lyophilized with 100% acetonitrile and is supplied as a powder. Reconstitute with 0.1 ml DI water for a final concentration of 1 mg/ml.
StorageMaintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C.
PrecautionsThis product is for research use only. Not for use in diagnostic or therapeutic procedures.
Protein Information
Name RAB23
Function The small GTPases Rab are key regulators of intracellular membrane trafficking, from the formation of transport vesicles to their fusion with membranes. Rabs cycle between an inactive GDP-bound form and an active GTP-bound form that is able to recruit to membranes different set of downstream effectors directly responsible for vesicle formation, movement, tethering and fusion. Together with SUFU, prevents nuclear import of GLI1, and thereby inhibits GLI1 transcription factor activity. Regulates GLI1 in differentiating chondrocytes. Likewise, regulates GLI3 proteolytic processing and modulates GLI2 and GLI3 transcription factor activity. Plays a role in autophagic vacuole assembly, and mediates defense against pathogens, such as S.aureus, by promoting their capture by autophagosomes that then merge with lysosomes.
Cellular Location Cell membrane; Lipid-anchor; Cytoplasmic side. Cell membrane Cytoplasm. Cytoplasmic vesicle, autophagosome. Endosome membrane. Cytoplasmic vesicle, phagosome. Cytoplasmic vesicle, phagosome membrane; Lipid-anchor; Cytoplasmic side. Note=Recruited to phagosomes containing S.aureus or M.tuberculosis
Research Areas
Citations (0)

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The protein encoded by this gene belongs to the small GTPase superfamily, Rab family. It may be involved in small GTPase mediated signal transduction and intracellular protein transportation. Alternative splicing occurs at this locus and two transcript variants encoding the same protein have been identified.


Jenkins,D., Am. J. Hum. Genet. 80 (6), 1162-1170 (2007)
Liu,Y.J., World J. Gastroenterol. 13 (7), 1010-1017 (2007)
Evans,T.M., Traffic 4 (12), 869-884 (2003)
Marcos,I., Int. J. Mol. Med. 12 (6), 983-987 (2003)

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$ 80.00
Cat# BP1456b
(40 western blots)
Availability: 2 weeks
Bulk Size
Seasonal Special on Bulk Order
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