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SIRT3 Antibody (N-term) Blocking Peptide

Synthetic peptide

Product Information
Primary Accession Q9NTG7
Clone Names 100507177
Peptide ID 100507177
Additional Information
Gene ID 23410
Other Names NAD-dependent protein deacetylase sirtuin-3, mitochondrial, hSIRT3, 351-, Regulatory protein SIR2 homolog 3, SIR2-like protein 3, SIRT3, SIR2L3
Format Synthetic peptide was lyophilized with 100% acetonitrile and is supplied as a powder. Reconstitute with 0.1 ml DI water for a final concentration of 1 mg/ml.
StorageMaintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C.
PrecautionsThis product is for research use only. Not for use in diagnostic or therapeutic procedures.
Protein Information
Name SIRT3
Synonyms SIR2L3
Function NAD-dependent protein deacetylase. Activates or deactivates mitochondrial target proteins by deacetylating key lysine residues. Known targets include ACSS1, IDH, GDH, SOD2, PDHA1, LCAD, SDHA and the ATP synthase subunit ATP5O. Contributes to the regulation of the cellular energy metabolism. Important for regulating tissue-specific ATP levels.
Cellular Location Mitochondrion matrix
Tissue Location Widely expressed.
Research Areas
Citations (0)

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This gene encodes a member of the sirtuin family ofproteins, homologs to the yeast Sir2 protein. Members of thesirtuin family are characterized by a sirtuin core domain andgrouped into four classes. The functions of human sirtuins have notyet been determined; however, yeast sirtuin proteins are known toregulate epigenetic gene silencing and suppress recombination ofrDNA. Studies suggest that the human sirtuins may function asintracellular regulatory proteins with mono-ADP-ribosyltransferaseactivity. The protein encoded by this gene is included in class Iof the sirtuin family. Two alternatively spliced transcriptvariants that encode different proteins have been described forthis gene.


Dransfeld, C.L., et al. Int. J. Oncol. 36(4):955-960(2010)Shulga, N., et al. J. Cell. Sci. 123 (PT 6), 894-902 (2010) :Shi, T., et al. J Dig Dis 11(1):55-62(2010)Kong, X., et al. PLoS ONE 5 (7), E11707 (2010) :Li, S., et al. PLoS ONE 5 (5), E10486 (2010) :

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$ 80.00
Cat# BP14573a
(40 western blots)
Availability: In Stock
Bulk Size
Seasonal Special on Bulk Order
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