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WNT3A Antibody (Center) Blocking Peptide

Synthetic peptide

     
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Product Information
Primary Accession P56704
Clone Names 100507254
Peptide ID 100507254
Additional Information
Gene ID 89780
Other Names Protein Wnt-3a, WNT3A
Format Synthetic peptide was lyophilized with 100% acetonitrile and is supplied as a powder. Reconstitute with 0.1 ml DI water for a final concentration of 1 mg/ml.
StorageMaintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C.
PrecautionsThis product is for research use only. Not for use in diagnostic or therapeutic procedures.
Protein Information
Name WNT3A
Function Ligand for members of the frizzled family of seven transmembrane receptors. Wnt-3 and Wnt-3a play distinct roles in cell-cell signaling during morphogenesis of the developing neural tube.
Cellular Location Secreted, extracellular space, extracellular matrix
Tissue Location Moderately expressed in placenta and at low levels in adult lung, spleen, and prostate
Research Areas
Citations (0)

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Background

The WNT gene family consists of structurally related geneswhich encode secreted signaling proteins. These proteins have beenimplicated in oncogenesis and in several developmental processes,including regulation of cell fate and patterning duringembryogenesis. This gene is a member of the WNT gene family. Itencodes a protein which shows 96% amino acid identity to mouseWnt3A protein, and 84% to human WNT3 protein, another WNT geneproduct. This gene is clustered with WNT14 gene, another familymember, in chromosome 1q42 region.

References

Sengupta, P.K., et al. J. Biol. Chem. 285(41):31164-31173(2010)Hubner, R., et al. Biochem. Biophys. Res. Commun. 400(3):358-362(2010)von Marschall, Z., et al. Biochem. Biophys. Res. Commun. 400(3):299-304(2010)Shin, H., et al. J. Dermatol. Sci. 58(2):91-96(2010)Jugessur, A., et al. PLoS ONE 5 (7), E11493 (2010) :

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$ 80.00
Cat# BP14596c
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