|Other Names||AH receptor-interacting protein, AIP, Aryl-hydrocarbon receptor-interacting protein, HBV X-associated protein 2, XAP-2, Immunophilin homolog ARA9, AIP, XAP2|
|Format||Synthetic peptide was lyophilized with 100% acetonitrile and is supplied as a powder. Reconstitute with 0.1 ml DI water for a final concentration of 1 mg/ml.|
|Storage||Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C.|
|Precautions||This product is for research use only. Not for use in diagnostic or therapeutic procedures.|
|Function||May play a positive role in AHR-mediated (aromatic hydrocarbon receptor) signaling, possibly by influencing its receptivity for ligand and/or its nuclear targeting.|
|Tissue Location||Widely expressed. Higher levels seen in the heart, placenta and skeletal muscle. Not expressed in the liver|
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The protein encoded by this gene is a receptor for arylhydrocarbons and a ligand-activated transcription factor. Theencoded protein is found in the cytoplasm as part of a multiproteincomplex, but upon binding of ligand is transported to the nucleus.This protein can regulate the expression of many xenobioticmetabolizing enzymes. Also, the encoded protein can bindspecifically to and inhibit the activity of hepatitis B virus.
Daly, A.F., et al. J. Clin. Endocrinol. Metab. 95 (11), E373-E383 (2010) :Stratakis, C.A., et al. Clin. Genet. 78(5):457-463(2010)Occhi, G., et al. Eur. J. Endocrinol. 163(3):369-376(2010)Igreja, S., et al. Hum. Mutat. 31(8):950-960(2010)Jugessur, A., et al. PLoS ONE 5 (7), E11493 (2010) :
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