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AIP Antibody (C-term) Blocking Peptide
Synthetic peptide
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
| Primary Accession | O00170 |
|---|---|
| Clone Names | 100507258 |
| Gene ID | 9049 |
|---|---|
| Other Names | AH receptor-interacting protein, AIP, Aryl-hydrocarbon receptor-interacting protein, HBV X-associated protein 2, XAP-2, Immunophilin homolog ARA9, AIP, XAP2 |
| Format | Peptides are lyophilized in a solid powder format. Peptides can be reconstituted in solution using the appropriate buffer as needed. |
| Storage | Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C. |
| Precautions | This product is for research use only. Not for use in diagnostic or therapeutic procedures. |
| Name | AIP |
|---|---|
| Synonyms | XAP2 |
| Function | May play a positive role in AHR-mediated (aromatic hydrocarbon receptor) signaling, possibly by influencing its receptivity for ligand and/or its nuclear targeting. |
| Cellular Location | Cytoplasm. |
| Tissue Location | Widely expressed. Higher levels seen in the heart, placenta and skeletal muscle. Not expressed in the liver |
Thousands of laboratories across the world have published research that depended on the performance of antibodies from Abcepta to advance their research. Check out links to articles that cite our products in major peer-reviewed journals, organized by research category.
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Provided below are standard protocols that you may find useful for product applications.
Background
The protein encoded by this gene is a receptor for arylhydrocarbons and a ligand-activated transcription factor. Theencoded protein is found in the cytoplasm as part of a multiproteincomplex, but upon binding of ligand is transported to the nucleus.This protein can regulate the expression of many xenobioticmetabolizing enzymes. Also, the encoded protein can bindspecifically to and inhibit the activity of hepatitis B virus.
References
Daly, A.F., et al. J. Clin. Endocrinol. Metab. 95 (11), E373-E383 (2010) :Stratakis, C.A., et al. Clin. Genet. 78(5):457-463(2010)Occhi, G., et al. Eur. J. Endocrinol. 163(3):369-376(2010)Igreja, S., et al. Hum. Mutat. 31(8):950-960(2010)Jugessur, A., et al. PLoS ONE 5 (7), E11493 (2010) :
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