|Other Names||Band 41-like protein 3, 41B, Differentially expressed in adenocarcinoma of the lung protein 1, DAL-1, Band 41-like protein 3, N-terminally processed, EPB41L3, DAL1, KIAA0987|
|Format||Synthetic peptide was lyophilized with 100% acetonitrile and is supplied as a powder. Reconstitute with 0.1 ml DI water for a final concentration of 1 mg/ml.|
|Storage||Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C.|
|Precautions||This product is for research use only. Not for use in diagnostic or therapeutic procedures.|
|Function||Tumor suppressor that inhibits cell proliferation and promotes apoptosis. Modulates the activity of protein arginine N- methyltransferases, including PRMT3 and PRMT5.|
|Cellular Location||Cytoplasm, cytoskeleton. Cell junction. Cell membrane; Peripheral membrane protein; Cytoplasmic side. Cytoplasm. Note=Detected in the cytoplasm of actively dividing cells|
|Tissue Location||Expressed at high levels in brain, with lower levels in kidney, intestine, and testis. Detected in lung|
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Provided below are standard protocols that you may find useful for product applications.
EPB41L3 is a critical growth regulator in the pathogenesis of meningiomas.
Dafou, D., et al. Neoplasia 12(7):579-589(2010)Rose, J.E., et al. Mol. Med. 16 (7-8), 247-253 (2010) :Hoy, J.L., et al. Mol. Cell. Neurosci. 42(4):466-483(2009)Kang, Q., et al. J. Cell. Sci. 122 (PT 8), 1091-1099 (2009) :Martins-de-Souza, D., et al. Eur Arch Psychiatry Clin Neurosci 259(3):151-163(2009)
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