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EPB41L3 Antibody (N-term) Blocking Peptide
Synthetic peptide
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
| Primary Accession | Q9Y2J2 |
|---|---|
| Clone Names | 100507277 |
| Gene ID | 23136 |
|---|---|
| Other Names | Band 41-like protein 3, 41B, Differentially expressed in adenocarcinoma of the lung protein 1, DAL-1, Band 41-like protein 3, N-terminally processed, EPB41L3, DAL1, KIAA0987 |
| Format | Peptides are lyophilized in a solid powder format. Peptides can be reconstituted in solution using the appropriate buffer as needed. |
| Storage | Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C. |
| Precautions | This product is for research use only. Not for use in diagnostic or therapeutic procedures. |
| Name | EPB41L3 (HGNC:3380) |
|---|---|
| Function | Tumor suppressor that inhibits cell proliferation and promotes apoptosis. Modulates the activity of protein arginine N- methyltransferases, including PRMT3 and PRMT5. |
| Cellular Location | Cytoplasm, cytoskeleton. Cell junction. Cell membrane; Peripheral membrane protein; Cytoplasmic side. Cytoplasm Note=Detected in the cytoplasm of actively dividing cells |
| Tissue Location | Expressed at high levels in brain, with lower levels in kidney, intestine, and testis. Detected in lung |
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Provided below are standard protocols that you may find useful for product applications.
Background
EPB41L3 is a critical growth regulator in the pathogenesis of meningiomas.
References
Dafou, D., et al. Neoplasia 12(7):579-589(2010)Rose, J.E., et al. Mol. Med. 16 (7-8), 247-253 (2010) :Hoy, J.L., et al. Mol. Cell. Neurosci. 42(4):466-483(2009)Kang, Q., et al. J. Cell. Sci. 122 (PT 8), 1091-1099 (2009) :Martins-de-Souza, D., et al. Eur Arch Psychiatry Clin Neurosci 259(3):151-163(2009)
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