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Mouse Clk1 Antibody (N-term) Blocking Peptide
Synthetic peptide
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
| Primary Accession | P22518 |
|---|---|
| Clone Names | 110316107 |
| Gene ID | 12747 |
|---|---|
| Other Names | Dual specificity protein kinase CLK1, CDC-like kinase 1, Protein kinase STY, Clk1, Clk, Sty |
| Format | Peptides are lyophilized in a solid powder format. Peptides can be reconstituted in solution using the appropriate buffer as needed. |
| Storage | Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C. |
| Precautions | This product is for research use only. Not for use in diagnostic or therapeutic procedures. |
| Name | Clk1 {ECO:0000312|MGI:MGI:107403} |
|---|---|
| Function | Dual specificity kinase acting on both serine/threonine and tyrosine-containing substrates (PubMed:1825055, PubMed:1986248, PubMed:9307018). Phosphorylates serine- and arginine-rich (SR) proteins of the spliceosomal complex and may be a constituent of a network of regulatory mechanisms that enable SR proteins to control RNA splicing. Phosphorylates: SRSF1, SRSF3 and PTPN1 (PubMed:8617202, PubMed:9307018). Regulates the alternative splicing of tissue factor (F3) pre-mRNA in endothelial cells (By similarity). |
| Cellular Location | Nucleus |
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Provided below are standard protocols that you may find useful for product applications.
Background
Phosphorylates serine-and arginine-rich (SR) proteins of the spliceosomal complex may be a constituent of a network of regulatory mechanisms that enable SR proteins to control RNA splicing. Phosphorylates serines, threonines and tyrosines.
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