|Other Names||Homeobox protein Hox-C13, Hoxc13, Hoxc-13|
|Format||Synthetic peptide was lyophilized with 100% acetonitrile and is supplied as a powder. Reconstitute with 0.1 ml DI water for a final concentration of 1 mg/ml.|
|Storage||Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C.|
|Precautions||This product is for research use only. Not for use in diagnostic or therapeutic procedures.|
|Function||Transcription factor which plays a role in hair follicle differentiation. Regulates FOXQ1 expression and that of other hair-specific genes.|
|Tissue Location||Expressed in differentiating keratinocytes. In the hair follicle lower matrix, expressed in all 3 hair shaft- forming compartments, i.e. cuticle, cortex and medulla. Expression stops sharply at the boundary with the germinal matrix compartment.|
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Sequence-specific transcription factor which is part of a developmental regulatory system that provides cells with specific positional identities on the anterior-posterior axis.
Mill, P., et al. PLoS Genet. 5 (11), E1000748 (2009) :Young, T., et al. Dev. Cell 17(4):516-526(2009)Katayama, K., et al. BMC Genet. 10, 60 (2009) :Grier, D.G., et al. Neonatology 96(1):50-60(2009)Owens, P., et al. Dev. Biol. 322(1):156-166(2008)
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