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>   home   >   Products   >   Peptides   >   Blocking Peptides   >   Mouse Ksr2 Antibody (C-term) Blocking Peptide   

Mouse Ksr2 Antibody (C-term) Blocking Peptide

Synthetic peptide

Product Information
Primary Accession Q3UVC0
Clone Names 110316205
Peptide ID 110316205
Additional Information
Other Names Kinase suppressor of Ras 2, Ksr2 {ECO:0000312|MGI:MGI:3610315}
Format Synthetic peptide was lyophilized with 100% acetonitrile and is supplied as a powder. Reconstitute with 0.1 ml DI water for a final concentration of 1 mg/ml.
StorageMaintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C.
PrecautionsThis product is for research use only. Not for use in diagnostic or therapeutic procedures.
Protein Information
Name Ksr2 {ECO:0000312|MGI:MGI:3610315}
Function Location-regulated scaffold connecting MEK to RAF. Has very low protein kinase activity and can phosphorylate MAP2K1 at several Ser and Thr residues with very low efficiency (in vitro). Interaction with BRAF enhances KSR2-mediated phosphorylation of MAP2K1 (in vitro). Blocks MAP3K8 kinase activity and MAP3K8- mediated signaling. Acts as a negative regulator of MAP3K3- mediated activation of ERK, JNK and NF-kappa-B pathways, inhibiting MAP3K3-mediated interleukin-8 production (By similarity).
Cellular Location Cytoplasm {ECO:0000250|UniProtKB:Q61097}. Membrane {ECO:0000250|UniProtKB:Q61097}; Peripheral membrane protein {ECO:0000250|UniProtKB:Q61097}
Research Areas
Citations (0)

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Location-regulated scaffold connecting MEK to RAF. Blocks MAP3K8 kinase activity and MAP3K8-mediated signaling. Acts as a negative regulator of MAP3K3-mediated activation of ERK, JNK and NF-kappa-B pathways, inhibiting MAP3K3-mediated interleukin-8 production (By similarity).


Costanzo-Garvey, D.L., et al. Cell Metab. 10(5):366-378(2009)Dougherty, M.K., et al. Mol. Cell 34(6):652-662(2009)

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$ 80.00
Cat# BP14634b
(40 western blots)
Availability: In Stock
Bulk Size
Seasonal Special on Bulk Order
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