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PDE8A Antibody (Center) (L572) Blocking Peptide

Synthetic peptide

Product Information
Primary Accession O60658
Clone Names 70319150
Peptide ID 70319150
Additional Information
Gene ID 5151
Other Names High affinity cAMP-specific and IBMX-insensitive 3', 5'-cyclic phosphodiesterase 8A, PDE8A
Target/Specificity The synthetic peptide sequence used to generate the antibody AP1463c was selected from the Center region of human PDE8A. A 10 to 100 fold molar excess to antibody is recommended. Precise conditions should be optimized for a particular assay.
Format The synthetic peptide was lyophilized with 100% acetonitrile and is supplied as a powder. Reconstitute with 0.1 ml deionized water for a final concentration of 1 mg/ml.
StorageMaintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C.
PrecautionsThis product is for research use only. Not for use in diagnostic or therapeutic procedures.
Protein Information
Name PDE8A
Function Hydrolyzes the second messenger cAMP, which is a key regulator of many important physiological processes. May be involved in maintaining basal levels of the cyclic nucleotide and/or in the cAMP regulation of germ cell development.
Tissue Location Expressed in most tissues except thymus and peripheral blood leukocytes. Highest levels in testis, ovary, small intestine and colon
Research Areas
Citations (0)

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PDE8A plays a role in signal transduction by regulating the intracellular concentration of cyclic nucleotides. This phosphodiesterase, which has a high affinity for cAMP, may be involved in maintaining basal levels of the cyclic nucleotide and/or in the cAMP regulation of germ cell development.


Wu,P., Proc. Natl. Acad. Sci. U.S.A. 101 (51), 17634-17639 (2004)Gamanuma,M., Cell. Signal. 15 (6), 565-574 (2003)

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$ 80.00
Cat# BP1463c
(40 western blots)
Availability: In Stock
Bulk Size
Seasonal Special on Bulk Order
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