|Other Names||Ribosyldihydronicotinamide dehydrogenase [quinone], NRH dehydrogenase [quinone] 2, NRH:quinone oxidoreductase 2, Quinone reductase 2, QR2, NQO2, NMOR2|
|Format||Synthetic peptide was lyophilized with 100% acetonitrile and is supplied as a powder. Reconstitute with 0.1 ml DI water for a final concentration of 1 mg/ml.|
|Storage||Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C.|
|Precautions||This product is for research use only. Not for use in diagnostic or therapeutic procedures.|
|Function||The enzyme apparently serves as a quinone reductase in connection with conjugation reactions of hydroquinones involved in detoxification pathways as well as in biosynthetic processes such as the vitamin K-dependent gamma-carboxylation of glutamate residues in prothrombin synthesis.|
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Provided below are standard protocols that you may find useful for product applications.
NQO2 (EC 22.214.171.124) is a flavoprotein that catalyzes the2-electron reduction of various quinones, redox dyes, and thevitamin K menadione. NQO2 predominantly uses dihydronicotinamideriboside (NRH) as the electron donor (summary by Wu et al., 1997[PubMed 9367528]).
Rose, J.E., et al. Mol. Med. 16 (7-8), 247-253 (2010) :Ji, L.D., et al. J. Pineal Res. 48(2):133-141(2010)Yu, K.D., et al. Breast Cancer Res. Treat. 118(3):647-649(2009)Choi, J.Y., et al. Clin. Cancer Res. 15(16):5258-5266(2009)Yu, K.D., et al. Hum. Mol. Genet. 18(13):2502-2517(2009)
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