VAMP3 Antibody (Center) Blocking Peptide
Synthetic peptide
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
Primary Accession | Q15836 |
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Clone Names | 100517011 |
Gene ID | 9341 |
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Other Names | Vesicle-associated membrane protein 3, VAMP-3, Cellubrevin, CEB, Synaptobrevin-3, VAMP3, SYB3 |
Format | Peptides are lyophilized in a solid powder format. Peptides can be reconstituted in solution using the appropriate buffer as needed. |
Storage | Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C. |
Precautions | This product is for research use only. Not for use in diagnostic or therapeutic procedures. |
Name | VAMP3 |
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Synonyms | SYB3 |
Function | SNARE involved in vesicular transport from the late endosomes to the trans-Golgi network. |
Cellular Location | Early endosome membrane; Single-pass type IV membrane protein. Recycling endosome membrane; Single-pass type I membrane protein. Synapse, synaptosome |
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Provided below are standard protocols that you may find useful for product applications.
Background
Synaptobrevins/VAMPs, syntaxins, and the 25-kDsynaptosomal-associated protein are the main components of aprotein complex involved in the docking and/or fusion of synapticvesicles with the presynaptic membrane. This gene is a member ofthe vesicle-associated membrane protein (VAMP)/synaptobrevinfamily. Because of its high homology to other known VAMPs, itsbroad tissue distribution, and its subcellular localization, theprotein encoded by this gene was shown to be the human equivalentof the rodent cellubrevin. In platelets the protein resides on acompartment that is not mobilized to the plasma membrane on calciumor thrombin stimulation.
References
Ban, H.J., et al. BMC Genet. 11, 26 (2010) :Fader, C.M., et al. Biochim. Biophys. Acta 1793(12):1901-1916(2009)Kean, M.J., et al. J. Cell. Sci. 122 (PT 22), 4089-4098 (2009) :Vassilopoulos, S., et al. Science 324(5931):1192-1196(2009)Luftman, K., et al. Biochem. Biophys. Res. Commun. 380(1):65-70(2009)
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