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CBX8 Antibody (Center) Blocking Peptide

Synthetic peptide

     
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Product Information
Primary Accession Q9HC52
Clone Names 100525023
Peptide ID 100525023
Additional Information
Gene ID 57332
Other Names Chromobox protein homolog 8, Polycomb 3 homolog, Pc3, hPc3, Rectachrome 1, CBX8, PC3, RC1
Format Synthetic peptide was lyophilized with 100% acetonitrile and is supplied as a powder. Reconstitute with 0.1 ml DI water for a final concentration of 1 mg/ml.
StorageMaintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C.
PrecautionsThis product is for research use only. Not for use in diagnostic or therapeutic procedures.
Protein Information
Name CBX8
Synonyms PC3, RC1
Function Component of a Polycomb group (PcG) multiprotein PRC1- like complex, a complex class required to maintain the transcriptionally repressive state of many genes, including Hox genes, throughout development. PcG PRC1 complex acts via chromatin remodeling and modification of histones; it mediates monoubiquitination of histone H2A 'Lys-119', rendering chromatin heritably changed in its expressibility.
Cellular Location Nucleus.
Research Areas
Citations (0)

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Background

Component of the Polycomb group (PcG) multiprotein PRC1 complex, a complex required to maintain the transcriptionally repressive state of many genes, including Hox genes, throughout development. PcG PRC1 complex acts via chromatin remodeling and modification of histones; it mediates monoubiquitination of histone H2A 'Lys-119', rendering chromatin heritably changed in its expressibility.

References

Dietrich, N., et al. EMBO J. 26(6):1637-1648(2007)Olsen, J.V., et al. Cell 127(3):635-648(2006)Stelzl, U., et al. Cell 122(6):957-968(2005)Obuse, C., et al. Genes Cells 9(2):105-120(2004)Levine, S.S., et al. Mol. Cell. Biol. 22(17):6070-6078(2002)

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$ 80.00
Cat# BP14665c
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