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CPT1A Antibody (C-term) Blocking Peptide

Synthetic peptide

Product Information
Primary Accession P50416
Clone Names 100525054
Peptide ID 100525054
Additional Information
Gene ID 1374
Other Names Carnitine O-palmitoyltransferase 1, liver isoform, CPT1-L, Carnitine O-palmitoyltransferase I, liver isoform, CPT I, CPTI-L, Carnitine palmitoyltransferase 1A, CPT1A, CPT1
Format Synthetic peptide was lyophilized with 100% acetonitrile and is supplied as a powder. Reconstitute with 0.1 ml DI water for a final concentration of 1 mg/ml.
StorageMaintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C.
PrecautionsThis product is for research use only. Not for use in diagnostic or therapeutic procedures.
Protein Information
Name CPT1A
Synonyms CPT1
Function Catalyzes the transfer of the acyl group of long-chain fatty acid-CoA conjugates onto carnitine, an essential step for the mitochondrial uptake of long-chain fatty acids and their subsequent beta-oxidation in the mitochondrion. Plays an important role in triglyceride metabolism.
Cellular Location Mitochondrion outer membrane; Multi- pass membrane protein
Tissue Location Strong expression in kidney and heart, and lower in liver and skeletal muscle
Research Areas
Citations (0)

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The mitochondrial oxidation of long-chain fatty acids isinitiated by the sequential action of carnitinepalmitoyltransferase I (which is located in the outer membrane andis detergent-labile) and carnitine palmitoyltransferase II (whichis located in the inner membrane and is detergent-stable), togetherwith a carnitine-acylcarnitine translocase. CPT I is the key enzymein the carnitine-dependent transport across the mitochondrial innermembrane and its deficiency results in a decreased rate of fattyacid beta-oxidation. Alternatively spliced transcript variantsencoding different isoforms have been found for this gene.


Gessner, B.D., et al. Pediatrics 126(5):945-951(2010)Collins, S.A., et al. Mol. Genet. Metab. 101 (2-3), 200-204 (2010) :Bailey, S.D., et al. Diabetes Care 33(10):2250-2253(2010)Song, S., et al. Mol. Cell. Endocrinol. 325 (1-2), 54-63 (2010) :Ruano, G., et al. Pharmacogenomics 11(7):959-971(2010)

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$ 80.00
Cat# BP14666b
Availability: In Stock
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