PLD2 Antibody (N-term) Blocking Peptide
Synthetic peptide
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
Primary Accession | O14939 |
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Clone Names | 100525111 |
Gene ID | 5338 |
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Other Names | Phospholipase D2, PLD 2, hPLD2, Choline phosphatase 2, PLD1C, Phosphatidylcholine-hydrolyzing phospholipase D2, PLD2 |
Format | Peptides are lyophilized in a solid powder format. Peptides can be reconstituted in solution using the appropriate buffer as needed. |
Storage | Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C. |
Precautions | This product is for research use only. Not for use in diagnostic or therapeutic procedures. |
Name | PLD2 (HGNC:9068) |
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Function | Function as phospholipase selective for phosphatidylcholine (PubMed:9582313). May have a role in signal-induced cytoskeletal regulation and/or endocytosis (By similarity). |
Cellular Location | Cell membrane {ECO:0000250|UniProtKB:P97813}; Lipid-anchor {ECO:0000250|UniProtKB:P97813} |
Tissue Location | Ubiquitous.. |
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Provided below are standard protocols that you may find useful for product applications.
Background
Phosphatidylcholine (PC)-specific phospholipases D (PLDs;EC 3.1.4.4) catalyze the hydrolysis of PC to produce phosphatidicacid and choline. Activation of PC-specific PLDs occurs as aconsequence of agonist stimulation of both tyrosine kinase and Gprotein-coupled receptors. PC-specific PLDs have been proposed tofunction in regulated secretion, cytoskeletal reorganization,transcriptional regulation, and cell cycle control.[supplied byOMIM].
References
Chae, Y.C., et al. Mol. Cell. Biol. 30(21):5086-5098(2010)Bailey, S.D., et al. Diabetes Care 33(10):2250-2253(2010)Knapek, K., et al. Mol. Cell. Biol. 30(18):4492-4506(2010)Tabatabaian, F., et al. J. Biol. Chem. 285(25):18991-19001(2010)Kang, D.W., et al. PLoS ONE 5 (8), E12109 (2010) :
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