|Other Names||Phospholipase A-2-activating protein, PLA2P, PLAP, PLAA, PLAP|
|Target/Specificity||The synthetic peptide sequence used to generate the antibody AP1466b was selected from the C-term region of human PLAA. A 10 to 100 fold molar excess to antibody is recommended. Precise conditions should be optimized for a particular assay.|
|Format||The synthetic peptide was lyophilized with 100% acetonitrile and is supplied as a powder. Reconstitute with 0.1 ml deionized water for a final concentration of 1 mg/ml.|
|Storage||Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C.|
|Precautions||This product is for research use only. Not for use in diagnostic or therapeutic procedures.|
|Function||Involved in the maintenance of ubiquitin levels.|
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Provided below are standard protocols that you may find useful for product applications.
PLAA stimulates human neutrophil aggregation and release of lysosomal enzymes, superoxide, and eicosanoids. It plays an important role in the regulation of specific inflammatory processes connected to such diseases as inflammatory bowel disease, pancreatitis, rheumatoid arthritis, and cutaneous malignant melanoma.
Koumanov,K., Cell Biol. Int. 27 (10), 871-877 (2003)Kozlenkov,A., J. Biol. Chem. 277 (25), 22992-22999 (2002)Beatty,B.G., Genomics 62 (3), 529-532 (1999)
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