FGF10 Antibody (C-term) Blocking Peptide
Synthetic peptide
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
Primary Accession | O15520 |
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Clone Names | 100507168 |
Gene ID | 2255 |
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Other Names | Fibroblast growth factor 10, FGF-10, Keratinocyte growth factor 2, FGF10 |
Format | Peptides are lyophilized in a solid powder format. Peptides can be reconstituted in solution using the appropriate buffer as needed. |
Storage | Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C. |
Precautions | This product is for research use only. Not for use in diagnostic or therapeutic procedures. |
Name | FGF10 |
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Function | Plays an important role in the regulation of embryonic development, cell proliferation and cell differentiation. Required for normal branching morphogenesis. May play a role in wound healing. |
Cellular Location | Secreted. |
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Provided below are standard protocols that you may find useful for product applications.
Background
The protein encoded by this gene is a member of thefibroblast growth factor (FGF) family. FGF family members possessbroad mitogenic and cell survival activities, and are involved in avariety of biological processes, including embryonic development,cell growth, morphogenesis, tissue repair, tumor growth andinvasion. This protein exhibits mitogenic activity for keratinizingepidermal cells, but essentially no activity for fibroblasts, whichis similar to the biological activity of FGF7. Studies of the mousehomolog of suggested that this gene is required for embryonicepidermal morphogenesis including brain development, lungmorphogenesis, and initiation of lim bud formation. This gene isalso implicated to be a primary factor in the process of woundhealing.
References
Stein, J.L., et al. Neuroimage 53(3):1160-1174(2010)Mostowska, A., et al. Birth Defects Res. Part A Clin. Mol. Teratol. 88(7):538-545(2010)Chattopadhyay, I., et al. Mutat. Res. 696(2):130-138(2010)Jugessur, A., et al. PLoS ONE 5 (7), E11493 (2010) :Yokoyama, K., et al. Nephron Clin Pract 115 (4), C237-C243 (2010) :
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