|Other Names||Fibroblast growth factor 10, FGF-10, Keratinocyte growth factor 2, FGF10|
|Format||Synthetic peptide was lyophilized with 100% acetonitrile and is supplied as a powder. Reconstitute with 0.1 ml DI water for a final concentration of 1 mg/ml.|
|Storage||Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C.|
|Precautions||This product is for research use only. Not for use in diagnostic or therapeutic procedures.|
|Function||Plays an important role in the regulation of embryonic development, cell proliferation and cell differentiation. Required for normal branching morphogenesis. May play a role in wound healing.|
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The protein encoded by this gene is a member of thefibroblast growth factor (FGF) family. FGF family members possessbroad mitogenic and cell survival activities, and are involved in avariety of biological processes, including embryonic development,cell growth, morphogenesis, tissue repair, tumor growth andinvasion. This protein exhibits mitogenic activity for keratinizingepidermal cells, but essentially no activity for fibroblasts, whichis similar to the biological activity of FGF7. Studies of the mousehomolog of suggested that this gene is required for embryonicepidermal morphogenesis including brain development, lungmorphogenesis, and initiation of lim bud formation. This gene isalso implicated to be a primary factor in the process of woundhealing.
Stein, J.L., et al. Neuroimage 53(3):1160-1174(2010)Mostowska, A., et al. Birth Defects Res. Part A Clin. Mol. Teratol. 88(7):538-545(2010)Chattopadhyay, I., et al. Mutat. Res. 696(2):130-138(2010)Jugessur, A., et al. PLoS ONE 5 (7), E11493 (2010) :Yokoyama, K., et al. Nephron Clin Pract 115 (4), C237-C243 (2010) :
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