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KCNQ3 Antibody (C-term) Blocking Peptide

Synthetic peptide

Product Information
Primary Accession O43525
Clone Names 100507269
Peptide ID 100507269
Additional Information
Gene ID 3786
Other Names Potassium voltage-gated channel subfamily KQT member 3, KQT-like 3, Potassium channel subunit alpha KvLQT3, Voltage-gated potassium channel subunit Kv73, KCNQ3
Format Synthetic peptide was lyophilized with 100% acetonitrile and is supplied as a powder. Reconstitute with 0.1 ml DI water for a final concentration of 1 mg/ml.
StorageMaintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C.
PrecautionsThis product is for research use only. Not for use in diagnostic or therapeutic procedures.
Protein Information
Name KCNQ3
Function Probably important in the regulation of neuronal excitability. Associates with KCNQ2 or KCNQ5 to form a potassium channel with essentially identical properties to the channel underlying the native M-current, a slowly activating and deactivating potassium conductance which plays a critical role in determining the subthreshold electrical excitability of neurons as well as the responsiveness to synaptic inputs.
Cellular Location Membrane; Multi-pass membrane protein.
Tissue Location Predominantly expressed in brain.
Research Areas
Citations (0)

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The M channel is a slowly activating and deactivatingpotassium channel that plays a critical role in the regulation ofneuronal excitability. The M channel is formed by the associationof the protein encoded by this gene and one of two related proteinsencoded by the KCNQ2 and KCNQ5 genes, both integral membraneproteins. M channel currents are inhibited by M1 muscarinicacetylcholine receptors and activated by retigabine, a novelanti-convulsant drug. Defects in this gene are a cause of benignfamilial neonatal convulsions type 2 (BFNC2), also known asepilepsy, benign neonatal type 2 (EBN2).


Bailey, S.D., et al. Diabetes Care (2010) In press :Gomez-Posada, J.C., et al. J. Neurosci. 30(27):9316-9323(2010)Rose, J.E., et al. Mol. Med. 16 (7-8), 247-253 (2010) :Talmud, P.J., et al. Am. J. Hum. Genet. 85(5):628-642(2009)Hahn, A., et al. Brain Dev. 31(7):515-520(2009)

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$ 80.00
Cat# BP14685b
(40 western blots)
Availability: In Stock
Bulk Size
Seasonal Special on Bulk Order
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