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TBX5 Antibody (N-term) Blocking Peptide

Synthetic peptide

Product Information
Primary Accession Q99593
Clone Names 100507287
Peptide ID 100507287
Additional Information
Gene ID 6910
Other Names T-box transcription factor TBX5, T-box protein 5, TBX5
Format Synthetic peptide was lyophilized with 100% acetonitrile and is supplied as a powder. Reconstitute with 0.1 ml DI water for a final concentration of 1 mg/ml.
StorageMaintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C.
PrecautionsThis product is for research use only. Not for use in diagnostic or therapeutic procedures.
Protein Information
Name TBX5
Function Involved in the transcriptional regulation of genes required for mesoderm differentiation. Probably plays a role in limb pattern formation.
Cellular Location Nucleus {ECO:0000255|PROSITE- ProRule:PRU00201}
Research Areas
Citations (0)

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This gene is a member of a phylogenetically conservedfamily of genes that share a common DNA-binding domain, the T-box.T-box genes encode transcription factors involved in the regulationof developmental processes. This gene is closely linked to relatedfamily member T-box 3 (ulnar mammary syndrome) on human chromosome12. The encoded protein may play a role in heart development andspecification of limb identity. Mutations in this gene have beenassociated with Holt-Oram syndrome, a developmental disorderaffecting the heart and upper limbs. Several transcript variantsencoding different isoforms have been described for this gene.


Shimada, M., et al. Hum. Genet. 128(4):433-441(2010)Bailey, S.D., et al. Diabetes Care 33(10):2250-2253(2010)Stirnimann, C.U., et al. J. Mol. Biol. 400(1):71-81(2010)Rose, J.E., et al. Mol. Med. 16 (7-8), 247-253 (2010) :Hong, K.W., et al. J. Hum. Genet. 55(6):336-341(2010)

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$ 80.00
Cat# BP14687a
(40 western blots)
Availability: In Stock
Bulk Size
Seasonal Special on Bulk Order
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