|Other Names||Cyclin-dependent kinase-like 1, Cdkl1|
|Format||Synthetic peptide was lyophilized with 100% acetonitrile and is supplied as a powder. Reconstitute with 0.1 ml DI water for a final concentration of 1 mg/ml.|
|Storage||Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C.|
|Precautions||This product is for research use only. Not for use in diagnostic or therapeutic procedures.|
|Cellular Location||Cytoplasm. Nucleus|
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Provided below are standard protocols that you may find useful for product applications.
CDKL1 is a member of a large family of CDC2 related serine/threonine protein kinases. The KKIALRE motif seems to be a cyclin binding region. CDKL1 was identified as a human homologue of cyclin dependent kinases by low stringency cloning studies. In view of its size and the conservation of a Thr-X-Tyr dual phosphorylation site motif in the region between kinase subdomains VII and VIII, it is more likely that CDKL1 corresponds to a MAP kinase family member. It was named after the amino acid sequence corresponding to the PSTAIRE motif of cdc2 (subdomain III).
Zambrowicz, B.P., et al. Proc. Natl. Acad. Sci. U.S.A. 100(24):14109-14114(2003)
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