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Mouse Ephb4 Antibody (Center) Blocking Peptide

Synthetic peptide

Product Information
Primary Accession P54761
Clone Names 110316152
Peptide ID 110316152
Additional Information
Gene ID 13846
Other Names Ephrin type-B receptor 4, Developmental kinase 2, mDK-2, Hepatoma transmembrane kinase, Tyrosine kinase MYK-1, Ephb4, Htk, Mdk2, Myk1
Format Synthetic peptide was lyophilized with 100% acetonitrile and is supplied as a powder. Reconstitute with 0.1 ml DI water for a final concentration of 1 mg/ml.
StorageMaintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C.
PrecautionsThis product is for research use only. Not for use in diagnostic or therapeutic procedures.
Protein Information
Name Ephb4
Synonyms Htk, Mdk2, Myk1
Function Receptor tyrosine kinase which binds promiscuously transmembrane ephrin-B family ligands residing on adjacent cells, leading to contact-dependent bidirectional signaling into neighboring cells. The signaling pathway downstream of the receptor is referred to as forward signaling while the signaling pathway downstream of the ephrin ligand is referred to as reverse signaling. Together with its cognate ligand/functional ligand EFNB2 plays a central role in heart morphogenesis and angiogenesis through regulation of cell adhesion and cell migration. EPHB4- mediated forward signaling controls cellular repulsion and segregation form EFNB2-expressing cells. Plays also a role in postnatal blood vessel remodeling, morphogenesis and permeability and is thus important in the context of tumor angiogenesis.
Cellular Location Cell membrane; Single-pass type I membrane protein
Tissue Location Expressed in various organ systems, including lung, liver, kidney, intestine, muscle and heart
Research Areas
Citations (0)

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Receptor for members of the ephrin-B family. Binds to ephrin-B2.

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$ 80.00
Cat# BP14714c
(40 western blots)
Availability: In Stock
Bulk Size
Seasonal Special on Bulk Order
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Ordering Information

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