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Mouse Gucy2f Antibody (Center) Blocking Peptide
Synthetic peptide
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
| Primary Accession | Q5SDA5 |
|---|---|
| Clone Names | 110316181 |
| Gene ID | 245650 |
|---|---|
| Other Names | Retinal guanylyl cyclase 2, Gucy2f |
| Format | Peptides are lyophilized in a solid powder format. Peptides can be reconstituted in solution using the appropriate buffer as needed. |
| Storage | Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C. |
| Precautions | This product is for research use only. Not for use in diagnostic or therapeutic procedures. |
| Name | Gucy2f {ECO:0000312|MGI:MGI:105119} |
|---|---|
| Function | Responsible for the synthesis of cyclic GMP (cGMP) in rods and cones of photoreceptors (By similarity). Plays an essential role in phototransduction, by mediating cGMP replenishment. May also participate in the trafficking of membrane-asociated proteins to the photoreceptor outer segment membrane (PubMed:17255100). |
| Cellular Location | Membrane {ECO:0000250|UniProtKB:P51842}; Single- pass type I membrane protein. Photoreceptor outer segment membrane; Single-pass type I membrane protein |
| Tissue Location | Retina.. |
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Provided below are standard protocols that you may find useful for product applications.
Background
Probably plays a specific functional role in the rods and/or cones of photoreceptors. It may be the enzyme involved in the resynthesis of cGMP required for recovery of the dark state after phototransduction (By similarity).
References
Schmidt, H., et al. J. Cell Biol. 179(2):331-340(2007)Baehr, W., et al. J. Biol. Chem. 282(12):8837-8847(2007)Corbo, J.C., et al. PLoS Genet. 1 (2), E11 (2005) :Shearstone, J.R., et al. Genomics 85(3):309-321(2005)Yamazaki, K., et al. Genomics 51(2):303-305(1998)
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