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CDH7 Antibody (N-term) Blocking Peptide
Synthetic peptide
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
| Primary Accession | Q9ULB5 |
|---|---|
| Clone Names | 70730027 |
| Gene ID | 1005 |
|---|---|
| Other Names | Cadherin-7, CDH7, CDH7L1 |
| Target/Specificity | The synthetic peptide sequence used to generate the antibody AP1471a was selected from the N-term region of human CDH7. A 10 to 100 fold molar excess to antibody is recommended. Precise conditions should be optimized for a particular assay. |
| Format | Peptides are lyophilized in a solid powder format. Peptides can be reconstituted in solution using the appropriate buffer as needed. |
| Storage | Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C. |
| Precautions | This product is for research use only. Not for use in diagnostic or therapeutic procedures. |
| Name | CDH7 |
|---|---|
| Synonyms | CDH7L1 |
| Function | Cadherins are calcium-dependent cell adhesion proteins. They preferentially interact with themselves in a homophilic manner in connecting cells; cadherins may thus contribute to the sorting of heterogeneous cell types. |
| Cellular Location | Cell membrane; Single-pass type I membrane protein |
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Provided below are standard protocols that you may find useful for product applications.
Background
CDH7 is a type II classical cadherin from the cadherin superfamily. This protein is a calcium dependent cell-cell adhesion glycoprotein comprised of five extracellular cadherin repeats, a transmembrane region and a highly conserved cytoplasmic tail. Type II (atypical) cadherins are defined based on their lack of a HAV cell adhesion recognition sequence specific to type I cadherins. Cadherins mediate cell-cell binding in a homophilic manner, contributing to the sorting of heterogeneous cell types and the maintenance of orderly structures.
References
Moore,R., Oncogene 23 (40), 6726-6735 (2004)Kools,P., Genomics 68 (3), 283-295 (2000)Shimoyama,Y., Biochem. J. 349 (PT 1), 159-167 (2000)Kremmidiotis,G., Genomics 49 (3), 467-471 (1998)
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