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>   home   >   Products   >   Peptides   >   Blocking Peptides   >   POLR2B Antibody (Center) Blocking Peptide   

POLR2B Antibody (Center) Blocking Peptide

Synthetic peptide

Product Information
Primary Accession P30876
Clone Names 100525096
Peptide ID 100525096
Additional Information
Gene ID 5431
Other Names DNA-directed RNA polymerase II subunit RPB2, DNA-directed RNA polymerase II 140 kDa polypeptide, DNA-directed RNA polymerase II subunit B, RNA polymerase II subunit 2, RNA polymerase II subunit B2, POLR2B
Format Synthetic peptide was lyophilized with 100% acetonitrile and is supplied as a powder. Reconstitute with 0.1 ml DI water for a final concentration of 1 mg/ml.
StorageMaintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C.
PrecautionsThis product is for research use only. Not for use in diagnostic or therapeutic procedures.
Protein Information
Function DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Second largest component of RNA polymerase II which synthesizes mRNA precursors and many functional non-coding RNAs. Proposed to contribute to the polymerase catalytic activity and forms the polymerase active center together with the largest subunit. Pol II is the central component of the basal RNA polymerase II transcription machinery. It is composed of mobile elements that move relative to each other. RPB2 is part of the core element with the central large cleft, the clamp element that moves to open and close the cleft and the jaws that are thought to grab the incoming DNA template (By similarity).
Cellular Location Nucleus.
Research Areas
Citations (0)

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This gene encodes the second largest subunit of RNApolymerase II, the polymerase responsible for synthesizingmessenger RNA in eukaryotes. This subunit, in combination with atleast two other polymerase subunits, forms a structure within thepolymerase that maintains contact in the active site of the enzymebetween the DNA template and the newly synthesized RNA. [providedby RefSeq].


Rose, J.E., et al. Mol. Med. 16 (7-8), 247-253 (2010) :Michiels, S., et al. Carcinogenesis 30(5):763-768(2009)Tu, S., et al. Nat. Struct. Mol. Biol. 15(4):419-421(2008)Lee, J.H., et al. Mol. Cell. Biol. 28(2):609-618(2008)Yamaguchi, Y., et al. Genes Cells 12(7):863-875(2007)

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$ 80.00
Cat# BP14739c
(40 western blots)
Availability: In Stock
Bulk Size
Seasonal Special on Bulk Order
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